Pharmaceutics - Definitions Flashcards
1
Q
Define the Volume of Distribution
A
V = Amount in body / Concentration in plasma
2
Q
Define Kt
A
Tells us how rapidly the drug would leave the tissue if Ca fell to zero
3
Q
Define Clearance
A
The volume of fluid that is completely cleared of drug per unit time
4
Q
Define Extraction Ratio
A
The fraction of the drug passing by the liver that is eliminated (by metabolism or being excreted into bile)
5
Q
Define Hepatic Clearance
A
The volume of blood entering the liver from which all drug is cleared per unit time
