Pharma Tables 2 Flashcards
1
Q
What inhibits CYP3A4
A
furanocoumarins in grapefruit, conazoles and erythromycin (shapes dont matter)
2
Q
What induces CYP3A4
A
Echincea, St Johns Wort
3
Q
CYP34a is important in [x] toxicity
A
acetamenophin
4
Q
CYP34A is important in {x} metabolism
A
midazolam
5
Q
What CYP has the most polymorphism
A
CYP2D6
6
Q
What drugs are affected by CYP2D6
A
Opiods (codeine), metaprolol
7
Q
What drugs are affected by CYP2C19
A
azepams, clopidrogel, -prazoles
8
Q
What induces CYP2C19
A
St Johns Wort, Gingko
9
Q
What drugs are affected by CYP2D9
A
Warfarin, NSAIDS
10
Q
What induces CYP2c9
A
St Johns Wort, Gingko
11
Q
What two substances are relevant in CYP2E1 metabolism
A
Acetaminophen and Ethanol
