Pharma Small Test 1 PQ Flashcards
4 indications of crystalloids
- hypovol due to quicm fluid loss
- correction of dehydration
- maintanence of tissue perfusion
- correct Acid- Base and electrolyte disturbances
Chicken drug
20% sulfachloropyridazine sodium aqeous sln
Administration route
IV
name of method
Bratton- Marshall method
What are we testing?
PK of drug
Dehydration treatment
- what
Isotonic Crystalloid
hypovolaemia treatment
- how fast
- admin route
minutes, hours s
IV, IO
Dehydration treatment
- how fast
- admin route
1-2 days
mild: PO, SC
severe: IV
Dehydration treatment
- how fast
- admin route
1-2 days
mild: PO, SC
severe: IV
hypovol treatment
- what
1st: isotonic crystalloid
(10-20ml/kg bolus in 20 min)
if we need:
Colloid and/or hypertonic crystalloid
Bacteriocidal drugs
- Aminoglycosides
- streptomycin, neomycin - Polypeptides - bacitracin
- B lactones –> penicllins (amoxycillin, ampicillin)
Cephalosporins (cefoperazon,cefquinome)
Bacteriostatic drugs
- Tetracyclins - tetracycline, doxycycline
- Macrolides - erythromycin, clarithromycin
- Lincosamides - lincomycin, clindamycin
Bacteriostatic drugs
- Tetracyclins - tetracycline, doxycycline
- Macrolides - erythromycin, clarithromycin
- Lincosamides - lincomycin, clindamycin
4 indications of colloids
- hypovol shock
- hypoalbuminemia
- high cap permeability
- SIRS or sepsis
Characteristics of hypovolaemia
- IV fluid deficit
- Volume deficit
- quick reaction needed
Characteristics of dehydratiion
- IS and sometimes IC deficit
- Time for reaction
Crystalloid infusion types
- isotonic
- hypotonic
- hypertonic
Category A drugs
A - avoid
Vancomycin
Category B drugs
Flouroquinolones
3rd and 4th gen cephalosporins
4th- cefquinome
3rd- cefoperazone, ceftiofur
Category C drugs
1st and 2nd gen cephalosporins
1st- cephalexine, cephaprin
2nd - cefuroxime
protein synthesis inhibitors
aminoglycosides
maintenance formula
bodyweight (kg) x 10 x dehydration percentage
synergistic combo
lincomycin, spectinomycin
R1
0.1% sodium nitrate aq sln
R2
0.5% sodium sulfamate aq sln