pharma 2

Question 1

what are the 1st gen of cephalosporins

Answer 1

cefazolin and cephalexin

Question 2

what are the uses of 1st gen

Answer 2

uncomplicated cystitis / treatment for uti / cefazolin is used as a presurgical prophylaxis/ skin infection

Question 3

does the 1st gen of cephalosporins treat meningitis and why

Answer 3

no bec it doesnt cross the bbb

Question 4

does the 2nd gen treat meningitis and why

Answer 4

no it doesnt bec it doesnt cross the bbb

Question 5

uses of the 2nd gen

Answer 5

uti/ uncomplicated cystitis / upper resp infec / CAP

Question 6

which ones of the 3rd gen can pass the bbb

Answer 6

ceftriaxone and cefotaxine

Question 7

which ones of the 3rd gen is anti pseudomonal

Answer 7

ceftazedine and cefoperazone

Question 8

what is the treatment of the gonorrhea

Answer 8

cefatriaxone and azithromycin

Question 9

uses of 3rd gen

Answer 9

1. meningitis by cefatriaxone or cefotaxime 2. sepsis 3. uti 4. gonorrhea by IM single dose of the
   cefatriaxone plus oral dose of azithmycin 5. HAP and CAP 6.thyphoid fever by parenteral cefftriaxone or orally by cefotaxime