pharma Flashcards
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What is the prevalence of AAI cases compared to DAA cases?
107 cases of AAI and 25 cases of DAA
This indicates a significant difference in prevalence between the two diseases.
What is the average age of patients affected by AAI and DAA?
40.5 years for AAI and 38.5 years for DAA
Both diseases are prevalent in young women.
What percentage of AAI cases reported androgenetic alopecia?
95.23%
In contrast, only 24% of DAA cases reported androgenetic alopecia.
According to Rebora’s hypothesis, why is AAI more frequent in patients with androgenetic alopecia?
Patients have a high percentage of hair follicles in telogen and a low number in anagen with high mitotic activity
This suggests a relationship between hair follicle phases and AAI prevalence.
What does the hypothesis regarding ‘escape in telogen’ imply?
Some follicles could pass from anagen to telogen without immediate hair loss
This may lead to more widespread hair loss instead of bald patches.
What trichoscopic feature was documented in 95% of AAI patients?
Diffuse yellow dots
This feature was described by Tosti et al for the first time.
What is the diagnostic sensitivity for AAI based on the trichoscopic combination of yellow dots and/or short hairs?
96%
This was reported by Inui et al.
What are the characteristic trichoscopic features of DAA?
Black dots and diffuse yellow dots
The presence of these features is proportional to the severity of the disease.
What does the presence of black dots in DAA indicate?
Acute damage to the follicles
Black dots are not grouped to oval areas but are widespread across the scalp.
What was the most frequent pattern seen in AAI?
Empty yellow dots, empty yellow dots with vellus hair, and small hair in regrowth
Pigtail hair was also very frequent and almost exclusively found in AAI.
What percentage of AAI cases exhibited pigtail hair?
57.9%
Pigtail hair was found in only 20% of DAA cases.
What does the presence of pigtail hair signify in AAI?
Indicative of inflammatory damage
This condition causes hair to fall out and prevents regrowth from becoming longer and thicker.
How does the follicular inflammatory insult in DAA compare to AAI?
Greater in DAA than in AAI
This results in similar trichoscopic and histopathological features to classic patches of acute AA.
What was the most common trichoscopic sign in both AAI and DAA?
Presence of empty yellow dots
> 5 empty yellow dots in a 40× field were noted in 92% of DAA patients and 8.4% of AAI patients.
In patients with severe clinical presentation (grade III), how many DAA patients had >5 empty yellow dots?
23 patients (92%)
Only 9 AAI patients (8.4%) had >5 empty yellow dots.
