Pharma Flashcards

1
Q

Pharmacodynamics are the effect..

A

drugs have on the body

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2
Q

Pharmacokinetics are actions..

A

the body takes on drugs

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3
Q

ADME stands for

A

absorption, distribution, metabolism and excretion

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4
Q

Statins are used to..

A

lower LDL cholesterol
reduce heart attack
reduce stroke

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5
Q

Common statins are

A

Simvastatin
atorvastatin
fluvastatin

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6
Q

Statins work by..

A

slowing production of LDL in the liver so that more is taken from the body to produce bile

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7
Q

Side effects of statins

A

diarrhoea
headaches
nausea
myopathy
kidney damage

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8
Q

Considerations for statins

A

liver function
kidney function
pregnancy and breastfeeding
being over 70
liver disease
alcohol consumption
hypothyroidism

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9
Q

Levothyroxine is used to treat

A

hypothyroidism

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10
Q

Side effects of omeprazole are

A

headaches
diarrhoea
stomach pain

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11
Q

amlodipine works by

A

blocking Ca channels

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12
Q

amlodipine is used to treat

A

hypertension

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13
Q

Side effects of amlodipine

A

headaches
flushing
swollen ankles
feeling dizzy
tiredness

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14
Q

Why is age considered during prescription

A

eGFR should be above 90ml/min. This affects how quickly a drug is excreted, changing dosage and toxicity levels

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15
Q

Factors for human error

A

device or product design, physical working environment, physical demands, interruptions, distractions, hunger, stress

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16
Q

Policies to improve patient safety

A

NHS patient safety strategy
NHS improvement
CQC
NMC

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17
Q

The MCA states a person is unable to make a decision if

A

they cannot understand information
retain information for long enough
weigh up information
communicate their decision

18
Q

What information does a MAR sheet have

A

conditions of prescription, location, limitations and dosage

19
Q

What medications are time-critical

A

parenteral antibiotics
insulin
parkinsons
opioid analgesia
anticoagulants
antiepileptics

20
Q

Common uses for antibiotics

A

respiratory infections
skin infections
gastrointestinal infections
surgical prophylaxis

21
Q

When should prescribed antimicrobials be reviewed

A

after 48-72 hours

22
Q

What is common law based on

A

Principles of necessity, actions of duty of care - taken appropriately and proportionally

23
Q

The 4 principles of ethics

A

beneficence
autonomy
non-maleficence
justice

24
Q

Diazepam is used for

A

anxiety
muscle spasm
seizures
alcohol withdrawal symptoms
relaxant

25
Considerations for Diazepam
Liver and kidney function myasthenia gravis sleep apnoea depression personality disorder arteriosclerosis pregnancy age over 65
26
Common side effects of Diazepam
feeling sleepy or drowsy confusion coordination problems hand tremors jaundice hallucinations delusions unusual mood changes
27
Examples of SSRIs are
setraline fluoxetine citalopram
28
SNRI stands for
serotonin and norepinephrine reuptake inhibitors
29
SNRIs are used for
Depression and anxiety
30
What is the difference between SSRIs and SNRIs
they are newer and stronger, meaning their side effects can be stronger and overdose more dangerous
31
Side effects of antidepressants
feeling agitated nausea indigestion diarrhoea or constipation loss of appetite dizziness insomnia headaches loss of libido
32
Two main types of antipsychotics
first gen and second gen
33
First generation antipsychotics have stronger side effects than SGAs such as
movement disorders: dystonia tremor restlessness slurred speech
34
Common side effects for antipsychotics
drowsiness weight gain loss of libido
35
Lithium is used to treat
Bipolar
36
What does lithium require management of
salt and liquid levels regular blood tests for safe dosage
37
What is another serious side effect of antidepressants and antipsychotics aside from movement disorders
prolongs QT interval which can result in fainting and ventricular fibrillation
38
Opioids and benzos are prescription only drugs because
they are highly addictive and sedative
39
What is Methadone used for
Maintenance therapy or detoxification to switch from heroin End of life care Severe pain
40
The effects of Methadone are
Reducing withdrawal symptoms: shaking, shivering, flu-like symptoms
41
Common side effects of Methadone
constipation feeling sick feeling cold and sweaty feeling sleepy/dizzy
42
Nursing considerations for opioids and benzos
Lung/breathing problems drug/alcohol addiction arrhythmia low blood pressure seizures kidney/liver problems Myasthenia gravis Pregnancy