Pharm V1 Hesi Flashcards
Mega vitamin C
Ascorbic acid
Used to treat or prevent vitamin C deficiency and to treat scurvy
DO NOT TAKE with DM or if on a low salt/salt-free diet
May cause GI upset, take with food to prevent
Isotretinoin teratogenesis teaching
DO NOT TAKE if pregnant
No accurate means of determining whether an exposed fetus has been affected
Increases risk of spontaneous abortion and premature brith
Congenital malformations in an embryo or fetus
Craniofacial, cardiovascular, neurological, and thymic malformations
Pt must use TWO reliable forms of contraception simultaneously for one month before, during, and for one month after treatment
Medication guide (for Isotretinoin) must be given to a pt each time it is dispensed (read iPLEDGE carefully before signing)
Most notably used to treat moderate acne
Usually PO (capsules)
Accutane
Calcium acetate renal
Nephrotoxic
May cause renal calculi
May cause metabolic acidosis in pts with renal disease
Hypercalcemia may result after large doses in chronic renal failure
Use with caution
Used to treat hyperphosphatemia (high phosphate in the blood) in patients with end stage kidney disease who are on dialysis
Ciprofloxacin teaching
antimicrobial
Antibiotic, fluoroquinolone
Take as prescribed, even after feeling better
Increase fluid intake to reduce risk of urine crystals
Avoid caffeine (stimulant)
Advise pt that hypersensitivity rxn may occur even after first dose
Stop immediately and notify PHCP
Tendon ruptures can occur
Notify PHCP if pain or inflammation occurs
Avoid excessive sunlight or artificial UV light
Photosensitivity
Black Box Warning:
Contraindicated for use in patients with acute sinusitis, acute exacerbations of chronic bronchitis, and acute uncomplicated UTI
N/V/D
Oseltamivir use
Tamiflu
Treats and prevents the flu (anti-viral)
Usually PO (without regard to food)
Administration considerations
Must be given within 48 hrs of s/s onset
May be used prophylaxis
Drug is NOT replacement for annual flu vax (teaching point)
S/A effects
Headache
Pain
N/V/D
Rifampin hepatotoxic
Anti TB
Hepatotoxic - monitor ALT, AST, and bilirubin
Causes orange secretions
Avoid tyramine foods (wine, aged cheeses, red meat, etc.)
Causes GI upset, decreased oral contraceptive effectiveness, vision changes
Trimoxazole/TMP-SMZ effect
Trimethoprim-Sulfamethoxazole
Common brands: Bactrim, Sulfatrim
Abx: pneumonia, bronchitis, UTI, etc.
Sulfonamide (common sulfa allergy)
Antagonistic to anticoagulation, sulfonylurea, and cardiac arrhythmia meds
S/A effects
Crystalluria
Nephrotoxic
Photosensitivity
Vancomycin peak and trough
Treats staph
Peak should be immediate after IV administration
Trough should occur at half-life and before administration of next dose
About 4-6 hours
Takes longer for pts with renal impairment
Check peak 1-2 hours after end of infusion and check trough right before (within 30 minutes of) giving next dose (trough is lowest level where patient is still within the therapeutic range)
Trough 5-15mcg/ml
Peak 20-40mcg/ml
Diflucan liver studies
Fluconazole (anti-fungal)
Treats yeast infections
VERY hepatotoxic (oral antifungal agents are associated with a low incidence of acute liver injury and that it may be fatal, especially for the elderly.)
Monitor ALTs and ASTs and bilirubin
S/S: jaundice, dark urine, light colored stools
Anaphylaxis penicillin
Most common medication allergy
Anaphylaxis STOP immediately
Cross sensitivity
Cephalosporins
Carbapenems
Monobactams
Ribavirin for hepatitis C
Antiviral
Monotherapy is ineffective for treatment of chronic hepatitis C
Hepatotoxic
Nephrotoxic
Important to educate about compliance
Prolonged therapy
Inhale or PO
Amlodipine evaluation
Antihypertensive
Ca channel blocker
Monitor BP and HR
Furosemide cramps
Loop diuretic
K+ wasting
S/A effects
Nephrotoxic
Ototoxic
Hypotension
Hypokalemia (muscle pain, cramps, and fatigue)
Clopidogrel hold
Antiplatelet
Increases risk of bleeding
Hold 5-7 days before any procedure where there is a high risk of bleeding
Rosuvastatin evaluate effect
Type of atorvastatin
Lowers LDL
Levels
Cholesterol <200
Triglycerides <150
LDL <100
HDL >50
Monitor LFTs and kidney function
Increased risk of rhabdomyolysis
Nitroglycerin (NTG) transdermal patch treat pain
Apply to hair-free skin
Remove patch after 12-14 hours and wash area with soap and water
Rotate patch sites
Remove patch before defibrillation or MRI (because it is metal)
When stopping, gradually reduce dose and frequency for 4-6 weeks
IV mls/hour
IV mL/hour IV gtts/minute
*Drip factor is how many drips per mL
*Drip factor is always a whole number
*Micro Drip tube has constant drip factor of 60 drops/mL
The MD orders your patient to start an IV Heparin drip at 18 units/kg/hr and to administer a loading bolus
dose of 30 units/kg IV before initiation of the drip. You’re supplied with a Heparin bag that reads 25,000
units/500 mL. The patient weighs 172 lbs. What is the flow rate you will set the IV pump at (mL/hr), and
how many units will be administered for the IV bolus?
Phenazopyridine
Analgesic-acting to relieve pain.
Used to relieve pain of UTI
Digoxin toxicity electrolytes
Therapeutic Range 0.8-2.0
Hypokalemia increases effect of digoxin toxicity
Normal K+ range 3.5-5.0
Tamsulosin BPH/reproductive/renal
Used to treat BPH and renal calculi to improve urine flow
Not indicated for use in women, only men
Screen for prostate cancer (s/s similar to BPH)
S/A effects
Priapism and low BP