Pharm Toxicology Flashcards

1
Q

Cornea: whorl k

A
Chloroquine
Hydroxychloroquine
Amiodarone
Indomethacin
Tamoxifen
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2
Q

Cornea: dry eye

A

BAK (incl glaucoma meds)

Anti-cholinergics

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3
Q

Cornea: SPK

A
Isotretinoin/accutane
Topical aminoglycosides (TobraGent)
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4
Q

Cornea: endo/descemet’s pigment

A

Promethazine/phenergan
Chlorpromazine
Thioridazine

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5
Q

Cornea: ocular chrysiasis

A

Gold salts in stroma

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6
Q

Cornea: delayed healing

A

Topical AND oral steroids

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7
Q

Lens: anterior subcapsular

A

Miotics (vacuoles)
Thioridazine
Amiodarone (deposits)
Chlorpromazine

*also atopic derm (shield)

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8
Q

Lens: PSC

A

Corticosteroids (dose dependent; esp in Hispanics)

*also x-rays/radiation

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9
Q

Conj and lids: Isotretinoin/Accutane

A

Blepharoconjunctivitis
Dryness
Lid edema

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10
Q

Conj and lids: subconj hemorrhage

A

NSAIDs
Coumadin
Clopidogrel (plavix)
Dipyridamole (~aspirin)

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11
Q

Conj and lids: sulfonamides

A

SJS

Lid edema

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12
Q

Conj and lids: pigmented cysts

A

Tetracyclines

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13
Q

Conj and lids: subconj hemorrhage and conj hyperemia

A

Viagra (sildenafil)

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14
Q

Conj and lids: prostaglandin analogs

A

Conj hyperemia
Incr growth/pigmentation of lashes
Incr pigmentation of periorbital skin

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15
Q

Conj and lids: tamiflu

A

Conjunctivitis (1%)

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16
Q

Lacrimal system: anticholinergic effects

A

Anticholinergics: STop ACH
Antidepressants: TCAs = amitriptyline, imipramine
Antihistamines: chlorpheniramine, brompheniramine, diphenhydramine, promethazine (phenergan)
Antipsychs: chlorpromazine, thioridazine

17
Q

Pupil size: mydriasis

A

Anticholinergics (STop ACH, antihistamines, antidepressants, antipsychs)

Dopamine agonists: methylphenidate & dextroamphetamine (ADHD), amantadine & bromocriptine (Parkinson’s)

18
Q

Pupil size: miosis

A

Opiates: morphine, heroine, codeine

AChase inhibitors: MG and Alzheimers drugs (edrophonium, neostigmine, echothiophate, pyridostigmine, donepezil)

19
Q

EOMS, eye movements: nystagmus

A

Phenytoin (dilantin)
Phenobarbital (luminal)
Salicylates = NSAIDs
Alcohol: end-point

20
Q

EOMS, eye movements: diplopia

A

Antidepressants
Antianxiety
Phenytoin

21
Q

EOMS, eye movements: smooth pursuits

A

Alcohol

22
Q

EOMS, eye movements: oculogyric crisis

A

Phenothiazines (chlorpromazine, thioridazine)

Cetirizine (zyrtec)

23
Q

Sclera, uvea: blue sclera

A

Minocycline

Corticosteroids

24
Q

Sclera, uvea: secondary angle closure

A

Topiramate (topamax): choroidal swelling moves uvea forward, also causes myopia

25
Q

Optic nerve: digoxin

A

Retrobulbar ON
BY color defects
Entopic/snowy