Pharm - TOXICOLOGY Flashcards

1
Q

Opiod overdose

A

naloxone, naltrexone

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2
Q

BZD overdose

A

flumazenil

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3
Q

Seizures

A

lorazepam, diazepam

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4
Q

Beta-blockers, Ca chnl blocker overdose

A

glucagon, insulin

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5
Q

Hypotension

A

NE, fluids

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6
Q

BRADYCARDIA

A

ATROPINE

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7
Q

TACHYCARDIA

A

B-BLOCKERS

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8
Q

ACETAMINOPHEN

A

N-ACETYLCYSTEINE (NAC)

NSAIDs lect: sulfahydryl drugs–NAC provides sulfhydryl to enhance non-toxic sulfation elimination of acetaminophen

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9
Q

ASPIRIN

A

FLUIDS, DEXTROSE, BICARBONATE

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10
Q

CO overdose

A

O2

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11
Q

CHLORINE, AMMONIA, SULFUR OXIDE (irritants) overdose

A

O2 + BRONCHODILATOR

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12
Q

CYANIDE overdose

A

KIT: (NA NITRATE + THIOSULFATE)

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13
Q

SYMPATHOMIMETICS overdose

A

VASODILATORS (PHENTOLAMINE, NITRATES of CA CHNL ANTAGONISTS for HTN), BENZODIAZEPINE (for agitation)

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14
Q

ORGANOPHOSPHATES (insecticides) overdose

A

ATROPINE, 2PAM

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15
Q

LEAD overdose

A

SUCCIMER, DIMERCAPROL, EDTA

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16
Q

ARSENIC overdose

A

DIMERCAPROL, SUCCIMER, PENICILLAMINE

17
Q

MERCURY overdose

A

DIMERCAPROL, SUCCIMER

18
Q

COPPER overdose

A

PENICILLAMINE (tx for WIlson’s disease)

19
Q

IRON overdose

A

DEFEROXAMINE, DESFERRAL

20
Q

RATTLESNAKE BITE

A

CROFAB ANTIVENIN

21
Q

OXIDIZING AGENTS (nitrogen oxides) overdose

A

METHYLENE BLUE

22
Q

HYDROGEN SULFIDE overdose

A

no specific antidote, but note that its toxicity & clinical features are similar to CYANIDE

23
Q

HYDROCARBON overdose

A

no specific tx, only supportive care