Pharm - TOXICOLOGY

Question 1

Opiod overdose

Answer 1

naloxone, naltrexone

Question 2

BZD overdose

Answer 2

flumazenil

Question 3

Seizures

Answer 3

lorazepam, diazepam

Question 4

Beta-blockers, Ca chnl blocker overdose

Answer 4

glucagon, insulin

Question 5

Hypotension

Answer 5

NE, fluids

Question 6

BRADYCARDIA

Answer 6

ATROPINE

Question 7

TACHYCARDIA

Answer 7

B-BLOCKERS

Question 8

ACETAMINOPHEN

Answer 8

N-ACETYLCYSTEINE (NAC)

NSAIDs lect: sulfahydryl drugs–NAC provides sulfhydryl to enhance non-toxic sulfation elimination of acetaminophen

Question 9

ASPIRIN

Answer 9

FLUIDS, DEXTROSE, BICARBONATE

Question 10

CO overdose

Answer 10

O2

Question 11

CHLORINE, AMMONIA, SULFUR OXIDE (irritants) overdose

Answer 11

O2 + BRONCHODILATOR

Question 12

CYANIDE overdose

Answer 12

KIT: (NA NITRATE + THIOSULFATE)

Question 13

SYMPATHOMIMETICS overdose

Answer 13

VASODILATORS (PHENTOLAMINE, NITRATES of CA CHNL ANTAGONISTS for HTN), BENZODIAZEPINE (for agitation)

Question 14

ORGANOPHOSPHATES (insecticides) overdose

Answer 14

ATROPINE, 2PAM

Question 15

LEAD overdose

Answer 15

SUCCIMER, DIMERCAPROL, EDTA

Question 16

ARSENIC overdose

Answer 16

DIMERCAPROL, SUCCIMER, PENICILLAMINE

Question 17

MERCURY overdose

Answer 17

DIMERCAPROL, SUCCIMER

Question 18

COPPER overdose

Answer 18

PENICILLAMINE (tx for WIlson’s disease)

Question 19

IRON overdose

Answer 19

DEFEROXAMINE, DESFERRAL

Question 20

RATTLESNAKE BITE

Answer 20

CROFAB ANTIVENIN

Question 21

OXIDIZING AGENTS (nitrogen oxides) overdose

Answer 21

METHYLENE BLUE

Question 22

HYDROGEN SULFIDE overdose

Answer 22

no specific antidote, but note that its toxicity & clinical features are similar to CYANIDE

Question 23

HYDROCARBON overdose

Answer 23

no specific tx, only supportive care