Pharm Test 3 Antidepressants Flashcards
1
Q
AMitriptyline Clomipramine Desipramine Imipramine Nortiptyline
A
TCAs
2
Q
Citalopram Escitalopram Sertraline Fluoxetine Fluvoxamine Paroxetine
A
SSRIs
3
Q
Venlafaxine
Duloxetine
A
SNRIs
4
Q
Bupropion
A
NDRI
5
Q
Nefazodone
Trazodone
A
SARIs
6
Q
Mirtazapine
A
NASSA
7
Q
Lithium
A
For Bipolar Disorders
MOA: Inositol depletino theory: inhibits polyphosphatse and monophosphatase blocking the regenration of inositol –> decreasePIP2 signaling cascade (Gq) –> decrease central adrenergic, muscarinec and 5HT neurotransmission
8
Q
Alternatives to Lithium for Bipolar
A
Valproate and carbamazepine;
Olanzapine and aripiprazole are used in maintanence treatment;
Quetiapine, Risperidone, Ziprasidone are used in mania or mixed episodes
Olanzapine and Fluoxetine is used in treatment oof depression associated with bipolar
Lamotrigine: maintanence treatment
9
Q
Isocarboxazid
Phenelzine
Tranylcypromine
Selegiline
A
MAO-Is
