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FA Rapid Review > Pharm side effects > Flashcards

Pharm side effects Flashcards

1
Q

adrenocortical insufficiency

A

HPA suppression secondary to glucorticord withdrawal

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2
Q

hot flashes

A

tamoxifen, clomiphene

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3
Q

hyperglycemia

A

tacrolimus, protease inhibitors, niacin, HCTZ, corticosteroids
Taking Pills Necessitates Having blood checked

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4
Q

hypothyroidism

A

lithium, amiodarone, sulfonamides

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5
Q

gynecomastia

A

spironolactone, digitalis, cimetidine, alcohol, estrogens, ketoconazole

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6
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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7
Q

diarrhea

A

metformin, erythromycin, colchicine, orlistat, acarbose

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8
Q

focal to massive hepatic necrosis

A

halothane, amanita phalloides, valproic acid, acetaminophen

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9
Q

hepatits

A

rifampin, isoniazid, pyrazinamide, statins, fibrates

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10
Q

pancreatitis

A

didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics

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11
Q

pseudomembranous colitis

A

clindamycin, ampicillin, cephalosporins

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12
Q

agranulocytosis

A

gangciclovir, clozapine, carbamazepine, colchicine, methimazole, PTU

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13
Q

aplastic anemia

A

carbamazepine, methimazole, NSAIDs, benzene, chloramphenicol, PTU

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14
Q

direct coombs positive hemolytic anemia

A

methyldopa penicillin

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15
Q

gray baby syndrome

A

chloramphenicol

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16
Q

hemolysis in G6PD deficiency

A

isoniazid, sulfonamides, dapsone, primaquine, aspirin, ibuprophen, nitrofurantoin

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17
Q

megaloblastic anemia

A

phenytoin, MTX, sulfa drugs

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18
Q

thrombocytopenia

A

heparin

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19
Q

thrombotic complications

A

OTC, HRT, combined with smoking

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20
Q

fat redistribution

A

protease inhibitors, glucocorticoids

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21
Q

gingival hyperplasia

A

phenytoin, CCB, cyclosporine

22
Q

hyperuricemia

A

pyrazinamide, thiazide, furosemide, niacin, cyclosporine

23
Q

myopathy

A

fibrates, niacin, colchicine, hydroxychloroquine, INFa, penicillamine, statins, glucocorticoids

24
Q

osteoporosis

A

corticosteroids, heparin

25
Q

photosensitivity

A

sulfonamides, amiodarone, tetracyclines, 5-FU

26
Q

rash (stevens johnson)

A

anti-epileptic drugs (lamotrigine), allopurinol, sulfa drugs, penicillin
Steven johnson has epileptic allergy to sulfa drugs and penicillin

27
Q

SLE like syndrome

A

sulfa, hydralazine, INH, procainamide, phenytoin, etanercept

SHIPPE

28
Q

teeth discoloration

A

tetracycline

29
Q

tendonitis, tendon rupture, cartilage damage

A

fluoroquinolones

30
Q

cinchonism

A

tinnitus, HA, deafness

quinidine, quinine

31
Q

parksinson like syndrome

A

antipsychotics, reserpine, metoclopramide

32
Q

seizures

A

INH (vitamin b6 deficiency), bupropion, imipenem/cilastatin, enfluane

33
Q

tardive dyskinesia

A

antipsychotics, metoclopramide

34
Q

diabetes insipidus

A

lithium, demeclocycline

35
Q

fanconi syndrome

A

expired tetracycline

36
Q

hemorrhagic cystitis

A

cyclophosphamide, ifosfamide

prevent with mesna

37
Q

interstitial nephritis

A

methicillin, NSAIDs, furosemide

38
Q

SIADH

A

carbamazepine, cyclophosphamide, SSRI

cant concentrate serum sodium

39
Q

dry cough

A

ace inhibitors

40
Q

pulmonary fibrosis

A

bleomycine amiodarone, busulfan, MTX

41
Q

antimuscarinic

A

atropine, TCA, H1 blockers, antipsychotics

42
Q

disulfram like reaction

A

metronidazole certain cephalosporin, griseofulvin, procarbazine, first gen sulfonylureas

43
Q

nephrotoxicity/ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin

cisplatin might respond to amifostine

44
Q

sulfa drugs

A

probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamide antibiotics, sulfasalazine, sulfaonylureas

45
Q

CYP450 inducers

A 
guinness, coronas, PBRS induce chronic alcoholism
griseofulvin
carbamazepine
phenytoin/phenobarbital
rifampin
st. johns wort
nevirapine
46
Q

CYP450 substrates

A

anti-epileptics
theophylline
warfarin
OCPs

47
Q

CYP450 inhibitors

A 
CRACK AMIGOS
cirpo
ritonavir
amiodarone
cimetidine
ketoconazole
acute alcohol abuse
macrolides (except azithromycin)
INH
grapefruit jiuce
sulfonamides
quinidine
48
Q

coronary vasospasm

A

cocaine, sumatriptan, ergot

49
Q

cutaneous flushing

A 
VANC
vancomycin
adenosine
niacin
CCB
50
Q

dilated cardiomyopathy

A

anthracyclines (doxo/daunor)

prevent with dexrazoxane

51
Q

torsades de pointes

A 
Class III and Ia
macrolides
antipsychotics
TCA
Tx with Mg

FA Rapid Review (3 decks)

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