Pharm SE/Others Flashcards

1
Q

Which drugs are affected by CYP34A?

A
  • Dabigatran
  • Rivaroxaban (xarelto)
  • Cilostazol
  • clopidogrel
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Contra: nasal polpys, bronchospams

A

ASA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Contra:CHF, thrombocytopenia, severe renal/liver impairment

A

Cilostazol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Dx-dx: antacids, quinolone, tetracycline

A

Iron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE: pulmonary syndrome, neurotoxicity, fever, leg cramps

A

Deferoxamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

dx-dx: metformin

A

B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

dx-dx: trimethoprine, MTX

A

folic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

SE: petechia, bone pain, splenomegaly

A

Filgastrim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

SE: secondary impact on iron deficiency, clotting: hypertension, thrombosis, seizures

A

Epoetin alfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

SE: vasculitis, skin necrosis

A

warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

SE: cyanosis, hypotension, flushing, rash

A

Vit K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

SE: alopecia, osteoporosis, skin necrosis

A

heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

contra: intra-cranial bleed, thrombocytopenia

A

heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

SE: increased AST/ALT

A

LMWH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SE: thrombocytopenia, rash, anemia, edema, fever

A

Fondapurinex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

contra: crcl

A

Dabigatran

17
Q

contra: pruritis, fever, bleeding

A

streptokinase

18
Q

SE: myopathy, muscle necrosis

A

Aminocaproic acid

19
Q

SE: reperfusion arrhythmias

A

Altepase

20
Q

Avoid with grapefruit juice

A

cilostazol

21
Q

contra: hemochromatosis, hemolytic anemia

A

Iron

22
Q

avoid high fat meals (increase effect)

A

Cilostazol

23
Q

SE: leukopenia

A

clopidogrel

24
Q

bioavailability increases with food

A

Rivaroxaban

25
Q

very moisture sensitive

A

Dabigatran

26
Q

omeprazole increases effect

A

Cilostazol

27
Q

atorvastatin decreases effect

A

clopidrogel