Pharm respiratory system ati Flashcards
Airflow disorder
Bronchodilator and anti-inflammatory agents
Bronchodilators
Beta2 adrenergic agonists, Methylxanthines, Inhaled anticholinergics
Anti-inflammatory agents
Glucocorticoid,leukotriene modifiers,mast cell stabilizers
Beta2 adrenergic agonists
Prototype: albuterol Short acting inhaler: levalbuterol Long acting inhaler: arformoterol, formoterol, salmeterol Long acting oral: terbutaline, albuterol Pregnancy risk: C
Methylxanthines
Prototype: Theophylline
Aminophylline (salt of theophylline)
Pregnancy risk: C
Inhaled anticholinergics
Prototype: ipratropium
Tiotropium
Pregnancy risk: B
Glucocorticoids
Prototype: Inhalation: Beclomethasone Oral: Prednisone Other: Inhalation: Budesonide, budesonide and formoterol, fluticasone and salmeterol, fluticasone, mometasone and formoterol Oral: prednisolone IV: Hydrocortisone, Methylprednisolone Pregnancy risk: C
Leukotriene modifiers
Prototype: Montelukast
Other:Zileuton , Zafirlukast
Pregnancy risk: B
Upper respiratory disorders
Antitussive combined with expectorant
Antitussives: opioids
Prototype: Codeine
Other: Hydrocodone
Pregnancy risk: C
Antitussives: Nonopioids
Prototype: Dextromethorphan
Other: Benzonatate, Diphenhydramine
Pregnancy risk:C
Expectorants
Prototype: Guaifenesin
Pregnancy risk: C
Mucolytics
Prototype: Acetylcysteine
Other: Hypertonic saline
Pregnancy risk: B
Decongestants
Prototype: Phenylephrine
Other: Ephedrine, Naphazoline, Pseudoephedrine
Antihistamines
1st generation H1 antagonists:Diphenhydramine, Promethazine, Dimenhydrinate
2nd generation H1 antagonists: Loratadine, Cetirizine, Fexofenadine, Desloratadine
Intranasal antihistamines: Azelastine, Olopatadine
Pregnancy risk: C