Pharm Quiz #5 Flashcards

1
Q

Fibromyalgia Treatments

A

Milnacipran
Pregabalin
Duloxetine

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2
Q

Milnacipran ADRs

A

Nausea
Vomiting
Headache

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3
Q

Muscle Relaxants

A

Cyclobenzaprine
Carisoprodol
Metaxalone
Baclofen

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4
Q

Intrathecal Medications

A

Ziconotide

Baclofen

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5
Q

Cyclobenzaprine ADRs

A

Urinary retention
Fatigue
Dry mouth

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6
Q

Cyclobenzaprine Drug Interactions

A

Alcohol
Selegiline
Rasagiline

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7
Q

Carisoprodol ADRS

A

Drowsiness
Depression
Dizziness

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8
Q

Metaxalone ADRs

A

Nausea
Vomiting
Headache

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9
Q

Methocarbamol ADRs

A

Nausea
Vomiting
Headache

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10
Q

Baclofen ADRs

A

Nausea
Vomiting
Confusion

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11
Q

Orphenadrine ADRs

A

Nausea
Vomiting
Headache

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12
Q

Ziconotide ADRs

A

Dizziness
Somnolence
Abnormal Gait

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13
Q

Intrathecal Baclofen ADRs

A

Dizziness
Somnolence
Hypotonia

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14
Q

Topical Analgesics

A

Methyl salicylate

Trolamine salicylate

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15
Q

Counterirritants

A

Menthol
Camphor
Capsaicin

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16
Q

Menthol ADRs

A

Skin irritation, contact dermatitis, heartburn

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17
Q

Capsaicin ADRs

A

Worsening ACEI cough
Burning
Stinging

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18
Q

Gout/Hyperuricemia Tx

A

Colchicine
Allopurinol
Rasburicase
Febuxostat

19
Q

Colchicine ADRs

A

Diarrhea

Throat pain

20
Q

Contraindicated with Colchicine

A

Strong 3A4 inhibitors
Ritonavir
Ketoconazole
Clarithromycin

21
Q

Drug Interactions with Allopurinol

A

Warfarin

Azathioprine

22
Q

Allopurinol ADRs

A

“RIN”
Rash
Increased LFTs
Nausea

23
Q

Probenecid ADRs

A

“BND”
Blood dyscrasias
Nausea
Dizziness

24
Q

Pegloticase ADRs

A

“PEG”
Chest pain
Ecchymosis
Gout flare

25
Q

Rasburicase ADRs

A

“HAM”
Hemolysis
Anaphylaxis
Methemoglobinemia

26
Q

Lesinurad

A

think kidneys!
Increased sCr
Renal failure
Kidney stones

27
Q

Drug Interactions for Lesinurad

A

Amlodipine

Sildenafil

28
Q

Rheumatologic Agents

Systemic Corticosteroids

A

Prednisone
Methylprednisolone
Prednisolone

29
Q

Systemic Corticosteroids

Short Term ADRs

A

Increased appetite
Fluid Retention
Weight gain

30
Q

Systemic Corticosteroids

Long Term ADRs

A

Osteoporosis
Cushing’s Syndrome
Diabetes

31
Q

Rheumatologic Agents

DMARDs

A

Methotrexate
Leflunomide
Sulfasalazine

32
Q

Methotrexate ADRs

A

Nausea
Diarrhea
Rash

33
Q

Methotrexate Contraindications

A

Pregnancy
Lactation
Alcoholism

34
Q

Leflunomide ADRs

A

Nausea
Diarrhea
Rash

35
Q

Hydroxychloroquine ADRs

A

Nausea
Diarrhea
Rash

36
Q

Leflunomide Contraindication

A

Pregnancy

37
Q

Leflunomide Warning

A

Hepatotoxicity

Monitor LFTs monthly x 6 months, then every 6-8 weeks

38
Q

Hydroxychloroquine Contraindications

A

Retinal or visual field changes

Long-term use in kids

39
Q

Hydroxychloroquine Warnings

A

Eye Effects (rare)
Edema
Atrophy
Abnormal macula pigmentation

40
Q

Sulfasalazine ADRs

A

Nausea
Abdominal discomfort
Photosensitivity

41
Q

Minocycline ADRs

A

“DRP”
Dizziness
Rash
Photosensitivity

42
Q

Rheumatologic Agents

Anti-TNF Drugs

A

Adalimumab
Etanercept
Infliximab

43
Q

Testing prior to Anti-TNF Drugs

A

TB Testing

44
Q

Anti-TNF ADRs

A

Infections!
URI
Sinusitis
Pharyngitis