Pharm- Parasympathetics Flashcards by Burke Crawford (IL CCOM 20)

Q

Acetylcholine (Miochol-E)

A

Muscarinic agonist

Limited use for glaucoma
Easily hydrolyzed

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Q

Bethanechol (Urecholine)

A

Muscarinic agonist

Stimulate GI motility and treat urinary retention

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Q

Pilocarpine (Salagen, Ocusert Pilo)

A

Muscarinic agonist

Treats glaucoma and xerostomia

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Q

Cevimeline (Evoxac)

A

Muscarinic agonist

Treats various types of salivary gland dysfunction

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Q

Edrophonium (Tensilon)

A

Reversible Cholinesterase inhibitors

Myasthenia gravis

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Q

Physostigmine (Eserine, Antilirium)

A

Reversible Cholinesterase inhibitors

Atropine overdose

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Q

Neostigmine (Prostigmin)

A

Reversible Cholinesterase inhibitors

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Q

Rivastigmine (Exelon)

A

Reversible Cholinesterase inhibitors

Alzheimer’s disease

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Q

Donepezil (Aricept)

A

Reversible Cholinesterase inhibitors

Alzheimer’s disease

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Q

Carbamate insecticides (Carbaryl)

A

Reversible Cholinesterase inhibitors

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Q

Parathion, Malathion, and other organophosphate insecticides

A

Irreversible Cholinesterase inhibitors

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Q

Sarin and other “nerve gasses”

A

Irreversible Cholinesterase inhibitors

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Q

Atropine

A

Muscarinic antagonist

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Q

Scopolamine

A

Muscarinic antagonist

More of a CNS depressant

Prevention of motion sickness and vertigo

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Q

Dicyclomine (Bentyl)

A

Muscarinic antagonist

Intestinal antispasmodic for the treatment of IBS

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Q

Glycopyrrolate (Robinul)

A

Muscarinic antagonist

Used in anesthesiology as a preop med to dry respiratory secretions and inhibit vagal reflexes

Q

Ipratropium (Atrovent)

A

Muscarinic antagonist

Administered by inhalation for the treatment of asthma and COPD

Q

Tiatropium (Spiriva)

A

Muscarinic antagonist

Q

Tolterodine (Detrol)

A

Muscarinic antagonist

Used for urinary incontinence

Q

Oxybutynin (Ditropan)

A

Muscarinic antagonist

Q

Tropicamide (Mydriacyl)

A

Muscarinic antagonist

Used to dilate the pupil for opthamilogic exam

Q

Solifenacin (VESIcare)

A

Muscarinic antagonist

Q

Botulinum toxin (Botox)

A

Toxins

Q

Pralidoxine/ 2Pam (Protopam)

A

Cholinesterase reactivator

DFP/ diisopropylfurophosphate/ isoflurophate and exhothiophate

Irreversible cholinesterase inhibitors

Pyridostigmine (Mestinon)

Reversible cholinesterase inhibitor