Pharm- Parasympathetics Flashcards
Acetylcholine (Miochol-E)
Muscarinic agonist
Limited use for glaucoma
Easily hydrolyzed
Bethanechol (Urecholine)
Muscarinic agonist
Stimulate GI motility and treat urinary retention
Pilocarpine (Salagen, Ocusert Pilo)
Muscarinic agonist
Treats glaucoma and xerostomia
Cevimeline (Evoxac)
Muscarinic agonist
Treats various types of salivary gland dysfunction
Edrophonium (Tensilon)
Reversible Cholinesterase inhibitors
Myasthenia gravis
Physostigmine (Eserine, Antilirium)
Reversible Cholinesterase inhibitors
Atropine overdose
Neostigmine (Prostigmin)
Reversible Cholinesterase inhibitors
Rivastigmine (Exelon)
Reversible Cholinesterase inhibitors
Alzheimer’s disease
Donepezil (Aricept)
Reversible Cholinesterase inhibitors
Alzheimer’s disease
Carbamate insecticides (Carbaryl)
Reversible Cholinesterase inhibitors
Parathion, Malathion, and other organophosphate insecticides
Irreversible Cholinesterase inhibitors
Sarin and other “nerve gasses”
Irreversible Cholinesterase inhibitors
Atropine
Muscarinic antagonist
Scopolamine
Muscarinic antagonist
More of a CNS depressant
Prevention of motion sickness and vertigo
Dicyclomine (Bentyl)
Muscarinic antagonist
Intestinal antispasmodic for the treatment of IBS