Pharm NCLEX Flashcards
Examples of Opioid Narcotics
Morphine Fentanyl (sublimaze) hydromorphone (Dilaudid) Meperdine (demerol) oxycodone (oxycotin) hydrocodone (vicodin) nalbuphine (nubain)
Action of Opioid Narcotics
Binds opiate receptors in CNS
decreases sensation of pain
decreases CN
indications for Opioid Narcotics
severe/acute/chronic pain
MI
dyspnea r/t pulmonary edema
side effects of Opioid Narcotics
impaired judgement decreased LOC decreased RR bradycardia n/v constipation urinary retention rash/itching
Non-opioid analgesics examples
acetaminophen (tylenol)
tramadol (ultram)
pregabalin (lyrica)
indication for non-opioid analgesics
mild/moderate pain
fever
peripheral neuropathy
fibromyalgia
side effects of non-opioid analgesics
liver failure edema dizzy drowsy suicidal thoughts
nursing interventions for non-opioid analgesics
AVOID ALCOHOL
nursing interventions for opioid narcotics
avoid alcohol
OD antagonists = naloxone
withdrawl med = methadone
examples of Benzodiazepimes (sedative, hypnotic, anxiolytics)
valium (diazepam) alprazolam (xanax) flurazepam (ativan) midazolam (versed) triazolam (halcion) chloridaepoxide (librium) zolpidem (ambien)
action of Benzos
increase GABA in brain
decrease nerve transmission
indication of Benzos
sedation/sleep decrease agitation/anxiety muscle relaxation impaired sleep conscius sedation DTs due to alc withdrawl
side effects of Benzos
decrease CNS increased fall risk decreased RR hypotension constipation/diarrhea n/v strange sleep behaviors
examples of Tricyclic antidepressants (anxiolytics)
imipamine (trofranil)
nortiptyline (pamelor)
amitryptyline (elavil)
deipramine (norpramin)
action of Tricyclic antidepressants (anxiolytics)
conseres seratonin and norepi
indication for Tricyclic antidepressants (anxiolytics)
endogenous depression neuropathic pain sleep apnea imipramine bed wetting OCD
side effects of Tricyclic antidepressants (anxiolytics)
sedation impotence cadiac arrhythmias edema decreased voiding tremoors orthostatic hypotension
nurse interventions for benzos
monitor liver fnction monitor decreased rr avoid alcohol addiction D/C slowly OD = flumazenil
nurse intervetnions for Tricyclic antidepressants (anxiolytics)
OD fatal suicide precautions 2-6 weeks for full effect monitor VS take at night r/t sedation d/c slowly dont give with other sedatives monitor for sun exposure and use sunscreen
examples of MAOIs (antidepressants)
Phenelzine (nardil) tranylcypromine (parnate) rasagiline (Azilect) selegiline (Eldepryl, Zelapar), isocarboxazid (Marplan), phenelzine (Nardil)
MAOI action
inhibits all neurotransmitter breakdown
MAOI indications
depression characterized by increased sleep, decreased hunger, chronic pain
MAOI side effects
HTN crisis w/ tyramine containing foods photosensitivity potentiates alcohol tacycardia dizziness insomina anorexia blurred vision drowsiness nauea headache impotence
MAOI nurse indications
many food/drug interactions
monitor output
may take 3-4 weeks to work
do not take with cns stimulants or OTC cold meds
examples of selective seratonin reuptake inhibitors (SSRIs) - most common antidepressants
fluoxetine (prozac) paroxetine (paxil) sertraline (zoloft) citalopram (celexa) escitalopram (lexapro)
SSRI action
conserves seratonin ONLY
no CV effects
SSRI indications
depression bipolar obesity eating disorders OCD
side effects of SSRIs
n/v
fatigue
weight increase/decrease
urinary retention
SSRI nurse interventions
suicidal recautions for 2-3 weeks minimum may take 4 weeks to take full effect take in morning monitor nutrition and fluids turns urine pink increased anticoag
examples of seratonin norepi reuptake inhibitors (SNRIs) - antidepressant
duloxetine (cymbalta)
venlafaxine (effexor)
SNRIs action
conserves seratonin & norepi
indications for SNRIs
depression
general anxiety
pain r/t diabetic neuropathy
nursing considerations for SNRIs
compete with other protein-binding drugs and increase function
examples of misc antidepressants & mood stabilizers
lithium carbonate (eskalith, lithobid)
lithium indications
mania
bipolar
lithium nursing considerations
increased fall risk
serum target = 0.8-1.2
encourage fluids
examples of traditional antipsychotics
thorazine (chlorpromainzine) low trilafon (perphenazine) haldol (haloperidol)
traditional antipsychotics action
block dopamine receptors at basal ganglia
traditional antipsychotics indications
acute and chronic psychosis
traditional antipsychotics side effects
akathisia (motor restlessness) dyskinesia (abnormal voluntary movement) dystonia (abnormal movement of face/mouth) parkinson's syndrome tardive dyskinesias ortho hypo constipation urine retention photosensitivity
traditional antipsych nursing interventions
check CBC
avoid alcohol and caffeine
slows child growth
use sunscreen
examples of atypical antipsychotics
clozapine (clozaril)
arlpioprazole (abilify)
risperidone (risperidol)
olanzapine (zyprexia)
atypical antipsychotics action
blocks dopamine
atypical antipsychotics indications
acute/chronic psychosis (bipolar, depression, autism, schitzo, tourettes)
nausea
anorexia
side effects of atypical antipsychotics
decreased LOC delerium ortho hypo dizziness photosensitivity constipation leukopenia
atypical antipsychotics nursing interventions
change positions slowly fall risk use sunscreen d/c slowly monitor liver and kidneys
examples of muscle relaxants
cyolobenzaprime (flexeril) carisoprodol (soma) mitaxalone (robaxin) baclofen (lioresal) dantrolene (dantroium)
action of muscle relaxants
majority act in CNS
some act directly and resemble GABA
muscle relaxants indications
diseases involving muscle spacicity
MS
side effects of muscle relaxants
euphoria lightheadedness dizziness fatigue muscle weakness n/v decreased LOC
muscle relaxant nurse indications
high fall risk
long half life
monitor response and adverse reactions
examples of anticonvulsant & anti-epileptic
phenytoin (dilantin) carbamazepine (tegretol) clonazepam (klonopin) fosphenytoin (cerebex) valporic acid (depakote) phenobarbitol (luminol) valium (diazepam) gabapentine (neurontin)
anticonvulsant & anti-epileptic action
decreased flow of calcium and sodium in neurons
decreased CNS
anticonvulsant & anti-epileptic indications
seizures
convulsions
epillepsy
neuropathic pain
anticonvulsant & anti-epileptic side effects
decreased RR gingival hyperplasia decreased LOC confusion slurred spech ataxia GI sensitivity
anticonvulsant & anti-epileptic nurse considerations
D/C slowly
monitor I&O
caution w meds that lower seizure threshold (MAOIs, anti-psychs)
take with food
no alcohol
good oral care
* dilantin: slow IV admin to avoid cardiac arrest; turns urine pink; never mix w any other meds only NS; gingivital hyperplasia
* depekote: never drink carbonated beverages!
examples of anti-parkinsons (anticholinergics)
benztropine (cogentin
procyclidine
trihexylphenidyl
dihenhydramine (benadryl)
action of anti-parkinsons (anticholinergics)
blocks ACH and decreases tremors and skeletal muscle response
anti-parkinsons (anticholinergics) indications
parkinsons symptoms: pill rolling, head bobbing
anti-parkinsons (anticholinergics) side effects
decreased emesis
decreased salivation
decreased GI and constipation
decreased mictruration
anti-parkinsons (anticholinergics) nurse indications
ortho hypo never D/C quickly monitor for urinary retetnion don't take with antacids take with food avoid CNS depressants
examples of anti-parkinson (dopaminergics)
bromocriptine pergolide pramipexole levodopa carbidopa (increases fxn of levodopa) entracapone (decreases dopa breakdown) selegiline tolcapone
side effects of anti-parkinsons (anticholinergics)
decreased LOC
dizziness
ataxia
anticholinergic effects(dry mouth, urinary retention, blurry vision)
examples of topical and local anistetics
benzocaine
lidocaine
prilocaine
tetracaine
action of topical and local anistetics
acts on local nerve fibers
indication for topical and local anistetics
suturing, dental procedures, diagnostic procedures
examples of NMBDs Neuromuscular blocking drugs
pancuronium (pavulon)
succinylcholine
vecuronium
NMBDs Neuromuscular blocking drugs indications
paralyzing effect but patient is conscious
assisted ventilation
minor surgery
herbal CNS depressants
capsacian/cayene pepper
kava kava
valerian
chamomile
examples of migraine drugs triptans & ergot alkaloids
sumatriptan (imitrex)
migranol
ADHD med examples
amphetamines: Adderall, Dexedrine, Dextrostat, Vyvanse
methamphetamine
methylphenidate: metadate, concerta, daytrana, ritalin, methylin, quillivant, focalin
non-stimulants: atomaxetine (strattera), clonidine (kapvay),guanfacine (intuniv)
examples of anorexiants (anti-obesity)
orlistat (xenical/Alli)
phentermine (lonamin)
action of anorexiants (anti-obesity)
orlistat: inhibits lipase/dietary fat uptake
lonamin: enhances metabolism similar to amphetamines
side effects of anorexians (anti-obesity)
increased BP uncontrolled HTN drug abuse anxiety headache GI distruptions
examples of vasoactive androgenic (pressors & inotropes & chronotropes) - may target alpha, beta or dopamine receptors
dobutamine dopamine epinephrine sphedrine fenoldopam norepinephrine phenylephrine
action of vasoactive androgenic (pressors & inotropes & chronotropes) - may target alpha, beta or dopamine receptors
response varies by dose generally: vasoconstriction (pressor) increased stroke volume (inotrope) increased HR (chronotrope)
indications for vasoactive androgenic (pressors & inotropes & chronotropes) - may target alpha, beta or dopamine receptors
MI shock COPD hypotension anaphylaxis HF
side effects of vasoactive androgenic (pressors & inotropes & chronotropes) - may target alpha, beta or dopamine receptors
increased BP headache excitement anti-cholinergic dysrhythmia HTn tachycardia
nursing considerations for vasoactive androgenic (pressors & inotropes & chronotropes) - may target alpha, beta or dopamine receptors
monitor Bp and peripheral pulse monitor UO monitor IV for infiltration tricyclics and MAOIs may cause HTn crisis antihistamines increase function
examples of alpha adronergic blockers
cardura (doxazosin) phenoocybenzamine pazosin terazosin phentolamine tamulosin
alpha adronergic blockers action
arerial and venous dilation
decreased BPH urinary obsruction
alpha adronergic blockers indications
diabetic neuropathy stroke prevention HTn BPH reverses extravvasation of pressors