PHARM: MODULE 9: MEDICATION FOR NEURO Flashcards
What effects does adrenergic agonists have on the body? (sympathetic response)
Act like norepinephrine/epinephrine. Produces a flight or fight response.
What do alpha 1 adrenergic agonist receptors do?
causes constriction in smooth muscles–> dilation of pupils
What are alpha 1 adrenergic agonist used to treat?
hypotension associated with shock
What do alpha 2 adrenergic agonist adrenergic agonist receptors do?
Blocks the release of norepinephrine/ epinephrine
What are alpha 2 adrenergic agonist used to treat?
hypertension
What do beta 1 adrenergic agonist receptors do?
Located in cardiac muscle–> Works to increase blood pressure and heart rate
What are beta 1 adrenergic agonist used to treat?
What are beta 1 adrenergic agonist used to treat?
Used to treat heart failure, cardiac arrest, shock.
What do beta 2 adrenergic agonist receptors do?
Dilates bronchioles.
What are beta 2 adrenergic agonist used to treat?
Used to treat asthma and premature labour contractions
What do non-selective beta adrenergic agonist do?
systemic vasodilation
What are non-selective beta adrenergic agonist used to treat?
used to treat anaphylaxis, asthma, cardiac arrest
used to treat anaphylaxis, asthma, cardiac arrest
blocks the adrenergic receptor sites, and indirectly blocks release of epinephrine
What effects do cholinergic agonists have on the body?
Acts like acetylcholine–> constricts pupils, vasodilation, bronchoconstriction, relax smooth muscle, decreased heart rate, decreased BP, increases gastric secretions
What effects do direct muscarinic agonists have on the body?
What effects do direct muscarinic agonists have on the body?
Increases smooth muscle tone, GI secretions, peristalsis and urination
What effects do indirect actylcholinesterase inhibitors have on the body?
Decreases the breakdown of acetylcholine by limiting and inhibiting acetylcholinesterase
What effect do anticholinergics have on the body?
Blocks the cholinergic receptors, produces a fight or flight response –> prohibits parasympathetic response
What are the actions of Adrenergic agonist?
Increase heart rate, dilate pupils, increase blood pressure, increase contractility, decrease gastric secretions and motility, contract smooth muscle, bronchodilation
What are the side effects of Adrenergic agonist?
Tachycardia, hypertension, dysrhythmias, Seizures and CNS excitement, vomiting, dry mouth, and nausea
What are the actions of Adrenergic Antagonist?
Decrease heart rate, constrict pupils, decrease blood pressure, decrease contractility, increase gastric secretions and motility, relaxation of smooth muscle, bronchoconstriction
What are the side effects of Adrenergic Antagonist?
Bradycardia, orthostatic hypotension, dysrhythmias
What are the actions of Cholinergic Agonist?
Decrease heart rate, increase gastric secretion, constrict pupils, increase gastric motility, relaxation of smooth muscles, bronchoconstriction
What are the DIRECT (muscarinic) side effects of Cholinergic Agonist?
Increased salivation, sweating, abdominal cramping, hypotension, fainting
What are the DIRECT (muscarinic) side effects of Cholinergic Agonist?
What are the INDIRECT (Acetylcholinesterase inhibitors) side effects of Cholinergic Agonist?
Increased salivation, increased muscle tone, urinary frequency, bronchoconstriction, bradycardia
What are the actions of Anticholinergics?
Increased heart rate, increased blood pressure, increased contractility, dilation of pupils, decreased secretions of GI tract, decreased gastric motility, constriction of smooth muscle, bronchodilation
What are the side effects of anticholinergics?
Dry mouth, constipation, urinary retention, increased heart rate. Initial excitement may progress to delirium and coma
What are precautions when administering Adrenergic Agonists medications?
Obtain complete health history, reason, vital signs, urinary output, cardiac output, assess nasal mucosa (Alpha 1)
What are nursing interventions when administering Adrenergic Agonists medications?
Closely monitor IV sites for extravasation, tuberculin syringe when administering, metered dose inhalation - shake well & wait 2 mins. Instill only proper # of drops. Monitor for side effects. Monitor breathing patterns. Observe for shortness of breath or audible wheezing. Responsiveness to light