Pharm HIV Meds Flashcards
HIV infection opt-out testing
Now you have to circle you dont want HIV testing or youll automatically be tested
Infections are most common in the south
HIV CD4
HIV seeks CD4 (T cells)
CD4: needed for immune system function
Healthy person:800-1200 CD4 cells
Gp120 to CD4 receptors
CD4 count vs HIV viral load
CD4 count >200 is best
HIV Viral load: undetected (<20) is goal
The higher the number the more virus in the blood
HIV meds
First were: HAART
Then: ART (antiretroviral therapy)
Then now their combo meds
HIV med indications
Usually HIV infection some for Hep B as well
Prophylactic healthcare workers:
-needles stick
HIV med contraindication
Severe allergy or intolerable toxicity
Cautions:
Statin drugs
Arrhythmia drugs
Hep C drugs
Anti-epilepsy drubs
TB drugs
HIV med AR
Short-term side effects/ new meds:
Main one: nausea
Headache
Vomiting
Diarrhes
Long-term management:
Renal function
Cholesterol panel
Treatment naive or established pt
Naive: freshly diagnosed
Ofetn: low CD4, weakened immune system
Assess
Head to toe, nutritional status, weight, VS, renal/liver, neuro, GI
Emotional status, financial status, support system
Bone mineral density:
VIT D and calcium
Drug interactions
Keep med list up to date
Allergies
Baseline labs
CBC: WBCs=infection
CMP: renal panel
Lipid profile: want a baseline
Pregnancy and HIV
Essential to begin ART or maintain during the entire pregnancy
Rare that the fetus gets HIV if med is used during pregnancy
ART is no garantee that virus will not be transmitted to fetus just reduces risk
PrEP (Pre-Exposure Prophylaxis)
Highly effective HIV prevention for high risk individuals
Trvada (TDF)
Descovy (TAF)
99% effective through sexual activity
How long to reach protection with PrEP
7 days after sex, sexual health history is important must ask
21 days for vaginal sex and IVDA
PrEP assessment
Baseline assessment
LABs:
HIV test (must be neg to use)
Renal Function
Liver fuction
PrEP SEs
Fatigue
HA
GI upset
Tends to go away
