pharm group questions Flashcards
which of the following is not a class of diuretics
- carbonic anhydrase inhibitors
- thiazide diuretics
- osmotic diuretic
- aldosterone agonist
aldosterone agonists
which of the following drugs potentiate rocuronium administration?
- furosemide
- HCTZ
- amiloride
- Tolvaptan
furosemide
what is the appropriate dose and drug given for MH?
dantrolene sodium 2.5mg/kg
which of the following is contraindicated with the administration of dantrolene sodium?
- calcium channel blockers
- nifedipine
- nicardipine
- felodipine
- all of the above
all of the above
which vitamin deficiency prolongs neuromuscular blockade
vitamin B
which supplement could greatly reduce the effect of drug agents that are metabolized by CYP450
st johns wort
which medication does garlic interact with
warfarin
what can you give for warfarin-associated bleeding
vitamin K
which of the oral antacids is least likely to be associated with pneumonitis if inhaled
sodium citrate
prior to induction of anesthesia you administer 40mg of famotidine in the preop area to decrease the risk of aspiration pneumonitis in your patient. what is the primary mechanism of action of this medication
reversibly binds and blocks parietal H2 receptors preventing H+ ion secretion
a patient with a 20 year history of T2DM presents to preop complaining of belching and bloating following meals. on several occasions, vomiting as occurred after a meal. Assessment reveals a diagnosis of diabetic gastroparesis with delayed gastric emptying. which drug would be most useful in this patient?
metoclopramide
which statements are true
1 - protonix is the most potent PPI
2 - protonix must be administered the night before surgery to produce and effect
3 - PPIs are the most effective drugs available for controlling gastric acidity and volume
4 - protonix is an H2 blocker
1 and 3
patient who have received bleomycin
are at high risk of pulmonary fibrosis
which of the following statements regarding MOA of chemotherapy drugs is correct?
taxanes are antimitotic agents that inhibit microtubule formation
which of the following side effects of chemotherapy are not related to myelosuppresion
alopecia
which of the following statements is true regarding administration and dosing of chemotherapeutics
repetitive dosing cycles are most often necessary to reach complete eradication of malignant cells
which of the following analgesics is least likely to contribute to serotonergic activity
morphine
with respect to the administration of direct or indirect acting sympathomimetics in the periop period, which drug class has the least concern for CV instability
SSRI
neurologic malignant syndrome is a rare side effect which mimics malignant hyperthermia. which of these medication classes is most responsible for this adverse effect
antipsychotics
which psychotropic medication can be smoked and therefore increase the incidence of a reactive airway
cannabis
what drug causes purple glove syndrome
fosphenytoin
what inhalation agent can provoke seizure like activity
sevoflurane
select all that apply to focal onset seizure 1 - it involves both brain hemispheres 2 - begins in a local cortical site 3 - awareness is impaired 4- consciousness is maintained
2 - begins in a local cortical site
3 - awareness is impaired
select all the meds that produce myoclonus
etomidate and propofol
niacin would be likely to exacerbate which of the following conditions
gout
which of the following drugs would be the best choice for a patient with liver disease
atorvastatin
what neuromuscular blocking drug is not recommended for patients on prolonged statin therapy
succinylcholine
which drug has the most severe adverse effects including rhabdo
lovastatin
what phase of immunosuppression would the CRNA most likely be involved in during organ transplantation
induction
glucocorticoids are used for all the following except
- autoimmune hemolytic anemia
- organ transplantation
- acute glomerulonephritis
- diabetes mellitus
DM
what are the most concerning side effects of cyclosporine
renal toxicity and HTN
what medication is used in the induction of immunosuppresion or for acute rejection
rabbit antithyomyocyte globulin - RATG
