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Advanced Pharm > pharm group questions > Flashcards

pharm group questions Flashcards

1
Q

which of the following is not a class of diuretics

  • carbonic anhydrase inhibitors
  • thiazide diuretics
  • osmotic diuretic
  • aldosterone agonist
A

aldosterone agonists

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2
Q

which of the following drugs potentiate rocuronium administration?

  • furosemide
  • HCTZ
  • amiloride
  • Tolvaptan
A

furosemide

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3
Q

what is the appropriate dose and drug given for MH?

A

dantrolene sodium 2.5mg/kg

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4
Q

which of the following is contraindicated with the administration of dantrolene sodium?

  • calcium channel blockers
  • nifedipine
  • nicardipine
  • felodipine
  • all of the above
A

all of the above

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5
Q

which vitamin deficiency prolongs neuromuscular blockade

A

vitamin B

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6
Q

which supplement could greatly reduce the effect of drug agents that are metabolized by CYP450

A

st johns wort

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7
Q

which medication does garlic interact with

A

warfarin

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8
Q

what can you give for warfarin-associated bleeding

A

vitamin K

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9
Q

which of the oral antacids is least likely to be associated with pneumonitis if inhaled

A

sodium citrate

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10
Q

prior to induction of anesthesia you administer 40mg of famotidine in the preop area to decrease the risk of aspiration pneumonitis in your patient. what is the primary mechanism of action of this medication

A

reversibly binds and blocks parietal H2 receptors preventing H+ ion secretion

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11
Q

a patient with a 20 year history of T2DM presents to preop complaining of belching and bloating following meals. on several occasions, vomiting as occurred after a meal. Assessment reveals a diagnosis of diabetic gastroparesis with delayed gastric emptying. which drug would be most useful in this patient?

A

metoclopramide

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12
Q

which statements are true
1 - protonix is the most potent PPI
2 - protonix must be administered the night before surgery to produce and effect
3 - PPIs are the most effective drugs available for controlling gastric acidity and volume
4 - protonix is an H2 blocker

A

1 and 3

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13
Q

patient who have received bleomycin

A

are at high risk of pulmonary fibrosis

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14
Q

which of the following statements regarding MOA of chemotherapy drugs is correct?

A

taxanes are antimitotic agents that inhibit microtubule formation

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15
Q

which of the following side effects of chemotherapy are not related to myelosuppresion

A

alopecia

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16
Q

which of the following statements is true regarding administration and dosing of chemotherapeutics

A

repetitive dosing cycles are most often necessary to reach complete eradication of malignant cells

17
Q

which of the following analgesics is least likely to contribute to serotonergic activity

A

morphine

18
Q

with respect to the administration of direct or indirect acting sympathomimetics in the periop period, which drug class has the least concern for CV instability

A

SSRI

19
Q

neurologic malignant syndrome is a rare side effect which mimics malignant hyperthermia. which of these medication classes is most responsible for this adverse effect

A

antipsychotics

20
Q

which psychotropic medication can be smoked and therefore increase the incidence of a reactive airway

A

cannabis

21
Q

what drug causes purple glove syndrome

A

fosphenytoin

22
Q

what inhalation agent can provoke seizure like activity

A

sevoflurane

23
Q 
select all that apply to focal onset seizure
1 - it involves both brain hemispheres
2 - begins in a local cortical site
3 - awareness is impaired
4- consciousness is maintained
A

2 - begins in a local cortical site

3 - awareness is impaired

24
Q

select all the meds that produce myoclonus

A

etomidate and propofol

25
Q

niacin would be likely to exacerbate which of the following conditions

A

gout

26
Q

which of the following drugs would be the best choice for a patient with liver disease

A

atorvastatin

27
Q

what neuromuscular blocking drug is not recommended for patients on prolonged statin therapy

A

succinylcholine

28
Q

which drug has the most severe adverse effects including rhabdo

A

lovastatin

29
Q

what phase of immunosuppression would the CRNA most likely be involved in during organ transplantation

A

induction

30
Q

glucocorticoids are used for all the following except

  • autoimmune hemolytic anemia
  • organ transplantation
  • acute glomerulonephritis
  • diabetes mellitus
A

DM

31
Q

what are the most concerning side effects of cyclosporine

A

renal toxicity and HTN

32
Q

what medication is used in the induction of immunosuppresion or for acute rejection

A

rabbit antithyomyocyte globulin - RATG

Advanced Pharm (11 decks)

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