Pharm GI Flashcards

1
Q

What fruit affects absorption of medications?

A

Grapefruit

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2
Q

What medications are used to treat constipation?

A

Laxatives
Cathartics

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3
Q

What kind of med can contribute to constipation

A

Diuretics

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4
Q

Name the 4 types of laxatives

A

Bulk-forming
osmotic
stimulants
stool softeners

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5
Q

What form does bulk-forming laxatives come as

A

A powder
Capsules
Wafer

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6
Q

Which laxative is safe for pregnant women?

A

Bulk- Forming

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7
Q

How long does it take for Bulk-Forming Laxative to work?

A

12hrs- 3 days

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8
Q

Give an example of Bulk-Forming Laxative

A

Psyllium(Metamucil)

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9
Q

Give example of a lubricant laxative

A

Suppositories
Mineral Oil

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10
Q

What does lubricant laxatives do?

A

Increase water to fecal mass to ease passage of stool

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11
Q

How long does it take a lubricant laxative to work

A

6-8hrs

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12
Q

What is an osmotic laxative?

A

draw water into the stool and irritate the bowel to increase peristalsis

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13
Q

Example of osmotic laxatives

A

Glycerin
Sorbitol
Milk of magnesia

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14
Q

How long does it take for osmotic laxatives take to work?

A

15-60 minutes

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15
Q

What contradictions are there for using osmotic laxatives

A

hypertension
edema
congestive heart failure (CHF)

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16
Q

What osmotic laxative is safe for ppl who have cardiovascular problems

A

Milk of magnesia

17
Q

What is the effect of stimulant laxatives

A

It stimulates peristalsis by irritating the bowel

18
Q

Example of stimulant laxative

A

Bisacodyl
Castor Oil
cascara sagrada

19
Q

Why can’t caster oil be used during pregnancy? and what does it cause in infants?

A

Can cause premature labor
During lactation can cause diarrhea in infants

20
Q

Side effects of bisacodyl

A

cramping
diarrhea
flatulence
nausea

21
Q

What does stool softeners do?

A

decrease consistency of stool

22
Q

What type of pt used stool softeners

A

Those with limited mobility

23
Q

Example of Stool Softener

A

Docusate(Colace)

24
Q

What are bowel evacuators

A

cleansing solution used before diagnostic tests to remove stool

25
Side effects of Bowel Evacuators
Bloating nausea fullness
26
Ex of bowel evacuators
Colyte GoLYTELY MoviPrep NuLYTELY, TriLyte Glycol ax MiraLAX
27
What are some causes of diarrhea?
chemicals, inflammation infections medications anxiety circulatory disorders
28
Antidiarrheals
Inhibit GI motility, decrease peristalsis, slow function of the GI system
29
Ex of antidiarrheals
Loperamide (Imodium) Diphenoxylate with atropine (Lomotil)
30
Side effects of diphenoxylate
dizziness, dry mouth, agitation, numbness, drowsiness, and tachycardia.
31
Absorbents
Absorb toxins or bacteria and coat walls of GI tract
32
Ex of absorbents
Bismuth (Pepto-Bismol): can turn tongue black Kaolin and pectin (kaopectate)