Pharm Foundations II Flashcards

1
Q

error of omission

A

something was LEFT OUT that is needed for safety

ex: failing to warn a patient about an important side effect with a new medication

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2
Q

error of commission

A

something was done INCORRECTLY

ex: prescribing bupropion to a patient with a history of seizures

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3
Q

evaluation and quality improvement: prospective

A

failure mode and effects analysis (FMEA) is a proactive method used to reduce the frequency and consequences of errors

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4
Q

evaluation and quality improvement: retrospective

A

a root cause analysis (RCA) is a retrospective investigation of an event that has already occurred, which includes reviewing the sequence of events that led to the error

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5
Q

evaluation and quality improvement: continuous

A

continuous quality improvement (CQI) is the goal for most health care settings
-lean and six sigmas

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6
Q

“do not use” abbreviations

A

U, IU, QD, QOD, trailing 0, lack of leading 0, MS, MSO4, MgSO4

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7
Q

high alert medications

A
  • anesthetics IV, inhaled (propofol)
  • antiarrhythmics IV (amiodarone)
  • anticoagulants. antithrombotics (heparin, warfarin)
  • chemotherapeutics (methotrexate)
  • epidural/ intrathecal drugs
  • hypertonic saline (> 0.9%)
  • immunosuppressants (cyclosporin)
  • inotropics (digoxin)
  • insulin
  • magnesium sulfate injection
  • neuromuscular blocking agents (vecuronium)
  • opioids
  • oral hypoglycemics (sulfonylureas)
  • parenteral nutrition
  • potassium chloride and phosphates for injection
  • sterile water for injection
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8
Q

code blue

A

patient requiring emergency medical care (typically for cardiac or respiratory arrest)

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9
Q

Common methods to reduce medication errors

A
  • avoid “do not use” abbreviations
  • tall man lettering
  • high alert medications
  • MTMs
  • med recs
  • indications and proper instructions on prescriptions
  • use metric system
  • do not identify meds based on packaging alone
  • avoid multiple dose vials
  • safe practices for emergency medications/crash carts
  • dedicate pharmacists to high risk areas
  • monitor for drug-food interactions
  • education
  • five rights of medication administration
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10
Q

use of technology and automated systems

A
  • computerized prescriber order entry and clinical decision support (CPOE)
  • barcoding
  • automated dispensing cabinets
  • patient controlled analgesia devices (PCA)
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11
Q

common types of hospital acquired infections

A
  • UTIs from indwelling catheters
  • bloodstream infections from IV lines (central lines highest risk) and catheters
  • surgical site infection
  • decubitus ulcers
  • hepatitis
  • c difficile
  • pneumonia (mostly due to ventilator use) and bronchitis
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12
Q

when to use soap and water (not alcohol based rubs)

A
  • before eating
  • after using the restroom
  • visible soil
  • caring for patient with c. diff or spore forming organisms
  • before caring for patient with food allergies
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13
Q

risk evaluation and mitigation strategies (REMS)
–> required by the FDA for some drugs

A
  • developed by manufacture
  • approved by FDA
  • ensures the benefits outweigh the risk of drug
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14
Q

medication guides
–> present important adverse events

A
  • FDA approved handouts
  • written in non technical language
  • part of the drugs labeling
  • dispense with original prescription and each refill
  • not necessary to dispense in hospital since pt is being monitored but should be available upon patient/family request
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15
Q

where to report side effects, adverse events and allergies

A

FDAs MedWatch program: FDA adverse event reporting system (FAERS)

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16
Q

drugs that cause photosensitivity

A
  • amiodarone
  • thiazide diuretics (HCTZ, chlorthalidone)
  • loop diuretics (furosemide, torsemide, bumetadine)
  • methotrexate
  • retinoids
  • quinolones (cipro, levoflox, moxifloxacin, ofloxacin)
  • st johns wort
  • sulfa antibiotics
  • tacrolimus
  • tetracyclines
  • voriconazole
17
Q

drugs associated with thrombotic thrombocytopenic purpura (TTP)
–> blood disorder in which clots form throughout the body

A
  • oral P2Y12 inhibitors (clopidogrel)
  • sulfamethoxazole
  • others (acyclovir, famciclovir, quinine, valacyclovir)
18
Q

drugs commonly associated with severe skin reactions

A
  • abacavir
  • allopurinol
  • carbamazepine
  • ethosuximide
  • lamotrigine
  • modafinil
  • nevirapine
  • penicillins
  • phenytoin
  • sulfamethoxazole