Pharm for GI Flashcards

1
Q

What are 5-aminosalicylates used for?

A

First line treatment of ulcerative colitis. 5-ASA derivatives inhibit the transcription factor NFkB that is required for activation of dendritic APCs.

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2
Q

What are the names of some 5-ASAs?

A

Sulfa group - Sulfasalazine
No sulfa group - Olsalazine, Balsalazide, Mesalamine

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