Pharm exam 4 Flashcards

1
Q

Community-associated infections?

A

An infection that is acquired by a person who has not been hospitalized or had a medical procedure (such as dialysis, surgery,
catheterization) within the past year

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2
Q

Healthcare-associated infections?

A

Health care–associated infections
Contracted in a hospital or institutional setting
Were not present or incubating in the patient on admission to the facility
More difficult to treat because causative microorganisms are often drug resistant and the most virulent
Occur in 10% of hospitalized patients MRSA most common
Also known as
nosocomial & iatrogen

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3
Q

Disinfectant?

A

Kills organisms
Used only on nonliving objects

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4
Q

Disinfectant?

A

Kills organisms
Used only on nonliving objects

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5
Q

Antiseptic

A

Generally only inhibits the growth of microorganisms but does not necessarily kill them
Applied exclusively to living tissue

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6
Q

Antibiotics

A

Medications used to treat bacterial infections
before beginning antibiotic therapy, the suspected areas of infection should be cultured to identify the causative organism and potential antibiotic susceptibilities

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7
Q

Antibiotic Therapy?

A

Empiric therapy: treatment of an infection before specific culture information has been reported or obtained

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8
Q

Definitive therapy?

A

Definitive therapy: antibiotic therapy tailored to treat organism identified with cultures

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9
Q

Prophylactic therapy?

A

Prophylactic therapy: treatment with antibiotics to prevent an infection, as in intraabdominal surgery or after trauma

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10
Q

Actions of Antibiotics:

A

Bactericidal: kill bacteria

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11
Q

Actions of Antibiotics: Bacteriostatic

A

Bacteriostatic: inhibit the growth of susceptible
bacteria, rather than killing them immediately; will eventually lead to bacterial death

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12
Q

Antibiotics used for?

A

Used for bacteria not viruses

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13
Q

Gram Positive

A

P for purple

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14
Q

Gram-negative

A

RED

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15
Q

Sulfonamides Blood test ?

A

WBC
RBC
Full panel coz it can suppress
your bone marrow.

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16
Q

Sulfonamides Side effect ?

A

crystalluria

17
Q

4 types of penicillins.

A

Natural penicillins
Penicillinase-resistant penicillins Aminopenicillins
Extended-spectrum penicillins

18
Q

Penicillins: Adverse Effects

A

Allergic reactions to the penicillins occur in 0.7% to 4% of treatment courses
Urticaria, pruritus, angioedema

19
Q

Cephalosporins have 5 generations:

A

-Semisynthetic antibiotics
-Structurally and pharmacologically related to penicillins
activity
-Bactericidal action
-Broad spectrum
-Divided into groups according to their antimicrobial activity

20
Q

Sharpie moment: Beta-lactam antibiotics include penicillins, cephalosporins, and related compounds.

A

Patients with a history of throat swelling or hives from penicillin should not receive cephalosporins because there could be cross-sensitivity because they are both Beta-lactams

21
Q

Sharpie moment. Cephalosporins: Adverse Effects:

A

Potential allergy exists with penicillin if a true allergy to penicillin exists.

22
Q

Sharipe moments, (Antibiotics).

A

Tetracyclines : They Bind (chelate) to Ca+++ and Mg++ and Al+++ ions. When these electrolytes bind to the antibiotic they become insoluble and complex. The antibiotic doesn’t work anymore.
Should not be used in children under age 8 or in pregnant/lactating women because tooth discoloration will occur if the drug binds to the calcium in the teeth

23
Q

Tetracyclines’ side effects.

A
  • Alteration in the intestinal flora may result in:
  • Superinfection (overgrowth of nonsusceptible organisms such as Candida)
24
Q

All oral antibiotics are absorbed better if taken with at least 6 to 8 ounces of water except penicillins

A
25
Q

Monitor patients taking penicillin for an allergic reaction for at least 30 minutes after administration

A
26
Q

A patient enters the emergency department with a draining wound. Once the patient is admitted and assessed, the priority nursing intervention is to

A

Culture the wound

27
Q

A patient enters the emergency department with a draining wound. Once the patient is admitted and assessed, the priority nursing intervention is to

A

Culture the wound

28
Q

When completing an admission assessment, the patient states that she is allergic to sulfa drugs. What will the nurse do next?

A

Ask the patient for more information about the allergic reaction she had.

29
Q

Aminoglycosides:

A

-Used to kill gram-negative bacteria
-Used for certain gram-positive infections that are resistant to other antibiotics

30
Q

Aminoglycosides

A

Cause serious toxicities:
Ototoxicity and nephrotoxicity are the most significant

31
Q

Quinolones

A

Also called fluoroquinolones