Pharm Exam 3 Review Flashcards
What are the combo hypertension medications?
ACEI/ ARB+ Thiazide
or
ACEI/ARB+ CCB
First line monotherapy for htn for african americans?
CCB or Thiazide
What are the benefits of aceis and arbs?
-decrease bp
-reduce plaque
What medications can increase HDL?
-statin
-niacin
fibrates
BP goal for most pts with htn?Who would this BP not apply to?
130/80
elderly
Initial txt for stage 1 HTN in a pt that does not have any risk factors (known ASCVD score)?
lifestyle modifications
Once pts with HTN have one risk factor start what?
monotherapy
What pts are higher risk of developing SAMS?
-Female
-low BMI
-older
-heavy exercise
-dehydration
-hypothyrodism
- renal dysfunction
- drug interactions
“tiny female marathon runner”
What would do for a pt with SAMS/
switch hydrophilic statin therapy
lower dose
medications that can cause 2ndry htn?
-NSAIDS
-ESTROGEN
-steroids
-antipsychotics
-atidepressants
-stimulants
What drug combos are the best at decreasing cardiovascular mortality rates?
acei or arb + ccb
or
acei or arb + thaizide
What is the first line treatment for htn?
acei, arb, ccb, thiazide/ diuretics
HTN emergency txt?
IV esmolol or nitroprusside or nicardipne or labetolo
Which pts do you want to rapidly decrease BP?
-aortic dissection
-hemorrhagic stroke
-preeclampsia
-pheochromocytoma
How long to decrease HTN emergency?
24-48 hrs
Stage 2 HTN txt?
depends if you need to decrase the SBP by 10 or 20.. determins mono or dual therapy
1st line pharm txt hypertriglyceridemia (<500)?
statins, lifestyle modifications
1st line txt for all HTN patients?
- dash diet (most effective)
- weight loss
- mediterranean diet
- aerobic activit (90-120 mins)
- salt intake (<1200)
- potassium intake (3500-5000)
- reduce ETOH intake
- DM management