Pharm Exam #3 (Diuretics) Flashcards

1
Q

What does furosemide treat?

A

heart -related edema, pulmonary edema, liver disease, kidney disease, hypertension

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2
Q

What is furosemide mode of action?

A

blocks reabsorption of sodium chloride & water at ascending Loop of Henle

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3
Q

What are some of the effects of furosemide?

A

excretion of potassium, magnesium, calcium, and rapid diuresis

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4
Q

Which key electrolyte imbalances should be monitored during furosemide therapy?

A

hyponatremia and hypokalemia

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5
Q

What should be monitored during Lasix (furosemide) treatment due to hypokalemia?

A

life threatening dysrhythmias

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6
Q

What are some side effects of Lasix (furosemide) therapy?

A

dehydration
hypotension
hyperglycemia
rash
ototoxicity

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7
Q

What time should Lasix be administered?

A

administer prior to 5pm so patient won’t wake up constantly to urinate

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8
Q

How fast should Lasix be administered?

A

administer slowly at 20mg/min

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9
Q

What should you assess and monitor on a patient being treated with Lasix?

A

monitor eyes, nose, electrolyte levels, and patient weight daily

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10
Q

What types of foods should patients eat while taking Lasix (furosemide)?

A

increase intake of potassium-rich foods (dark leafy greens, potatoes, avocados, cantaloupe, tomatoes)

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11
Q

Who is spironolactone contraindicated for?

A

patients with severe kidney failure

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12
Q

What does spironolactone treat?

A

heart failure and hypertension

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13
Q

What is spironolactone mode of action?

A

blocks aldosterone which promotes excretion of sodium and water while retaining potassium

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14
Q

Which lab value should be closely monitored during spironolactone therapy?

A

potassium

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15
Q

What type of food should patients avoid during spironolactone therapy?

A

salt substitutes (high in potassium)

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16
Q

What are some side effects of spironolactone therapy?

A

hyperkalemia
amenorrhea (lack of menstruation)
gynecomastia (increase in male breast size)
impotence (erectile dysfunction)

17
Q

What is mannitol used for?

A

edema, increased intracranial pressure, increased intraocular pressure

18
Q

What are side effects of mannitol?

A

pulmonary edema, heart failure, renal failure, phlebitis, dehydration, and sodium & potassium electrolyte imbalances

19
Q

Which medication increases serum osmolality which draws fluid from the intracellular space into the interstitial space as well as into the plasma or bloodstream?

A

mannitol, an osmotic diuretic

20
Q

What should you monitor during mannitol therapy?

A

weight, I&O, electrolyte levels, ICP = 10-15 mmhg, IOP = 10-21 mmhg (normal limits)