PHARM CV2 Flashcards
what do our class 1 arrhythmic drugs essentially do?
block sodium channels
from class 1 A-C, what are our three arrhythmic drugs?
A) Procainamide
B) Lidocaine
C) Flecainide
which class 1 drug is used for life-threatening ventricular arrhythmias? which is used to suppress existing ventricular arrhythmias?
procainaimide=life threatening ventricular arrythmias
lidocaine=suppressing existing ventricular arrythmias
which of our anti-arrhythmia drugs is contra-indicated with a corn allergy?
lidocaine
what are contraindications for most of our arrhythmia drugs?
complete heart blocks
what arrhythmia class are our beta blockers?
2; propranalol, metoprolol, atenolol
what is our class 3 arrhythmic? what does it do?
amiodarone; it inhibits alpha and beta stimulation affecting the sodium, potassium, and calcium channgels which PROLONGS AP AND REFRACTORY PERIODS; decreases AV conduction and sinus node function
when do we use amiodarone?
often for people with multiple comorbidities who are unstable, have recently recovered from an MI, and are spontaneously going into AFIB
who do we need to be cautious of when prescribing amiodarone?
people with thyroid disease
what are our class 4 arrhythmia drugs?
calcium channel blockers verapamil and diltiazem; work by dilating coronary arteries and decreasing oxygen demands
what are our indications for adenosine?
PSVT, pharmacologic stress testing
which of our anti-arrhythmic drugs is a naturally occurring nucleoside?
adenosine
how does adenosine work in stress testing vs. PSVT?
in stress testing: coronary vasodilation and increased blood flow in normal coronary arteries but does NOTHING to stenotic coronary arteries so that we can compare
PSVT: slows conduction through AV node
what are the four drugs we use for atrial fibrillation?
digoxin, beta blockers, calcium channel blockers diltiazem & verapamil
amiodarone ONLY if acute and many complications
which drug is our cardiac glycoside? what is its MOA?
digoxin; inhibits sodium potassium pump and both increases contractility AND suppresses AV node to decrease rate