Pharm Blessings last time ever AYO Flashcards
this is about to be a blast
PSYCH!
^^^^see what I did there^^^^
anyway, no, this is not about to be fun
are hallucinations a positive or negative psychosis symptom
positive
how do you treat positive psychosis symptoms?
WELL, historically, they use FGA if someone has only positive symptoms. BUT in class they said: SGA like risperidone [risperdal] or quetiapine [seroquel] So make of that what you will.
drugs that increase _______ cause sexual dysfunction in the 2nd gen antipsychotics
prolactin
does quetiapine [seroquel] increase prolactin levels?
no
the majority of the time, do we use FGA (first gen antipsych) or SGA (second gen antipsych)?
SGA
what are the 2 methods of giving risperidone [risperdal]?
PO or IM
disorganized speech, flat affect, and decreased short-term memory… positive or negative sx?
negative
what are the most prominent side effects of FGA
serious EPS*
sedation*
and more but who cares about those, i know i don’t
when on FGAs, you need to do an AIMS score every ___ months
6
What are the most prominent s/e of SGA?
metabolic*
what are the s/e of a dopamine antagonist?
uninhibited prolactin release
you have a patient with PD and agitation. what do you rx?
SGA like quetiapine [seroquel]
You have a pt with unipolar depression and hypomania. they want to know if Lurasidone [Latuda] or Quetiapine [Seroquel] is better for their mixed depressive symptoms?
Quetiapine [Seroquel]
less TD, less neuromusc sx, cheaper!
If on Clozapine [Clozaril], you need weekly blood tests to check for _______
agranulocytosis
T2DM hyperlipidemia obesity angina tobacco use are all relative c/i to what type of drug
SGA
elderly people on SSRIs have increased risk of what?
QTc prolongation
which SSRI drug has the biggest increased risk for QTc prolongation?
Citalopram [Celexa]
citalopram [celexa] + ziprasidone [geodon] causes what label of interaction?
X
how many psychotherapists does it take to change a light bulb?
Just one
as long as the lightbulb wants to change
pt is on lithium and halperidol [haldol] and has a new onset eye twitch. what’s going on?
med s/e
decrease Li
change to SGA like risperidone [risperdal]
do AIMS score
what is the average dose of halperidol [haldol]
4mg
TD is almost never seen before ______
and is usually seen after _________
not seen before 6 months
usually after 2-3y
after you fix TD, how long does it take to go away?
sometimes years
EEEEEEEEK
do FGA or SGA have an increased risk of CVD and hepatic/renal impairment?
SGA
are FGA or SGA more expensive?
SGA
just in general, _____% of people will fill their prescription by 2 weeks, and ____ will refill a second time
50
1/3
if you are on an SSRI and start Tramadol, you could get _____________
serotonin syndrome
WHEN I SAY increased heart rate, increased temp, agitation, hyperreflexes, confusion, and myoclonus YOU SAY _________
serotonin syndrome
how long does it take for fluoxetine [prozac] to clear from the system
6-8 weeks
What can tramadol cause in the elderly
seizures
THROWBACK BUT ALSO KIND OF RELATED:
what is the drug you rx for dementia in parkinson’s or alzheimer’s?
aricept
patient with dementia has increasing agitation.
what do you do?
“find the root cause. are they in pain? are they hungry?” - Maria Egger
“give ‘em the haldol” - Tom White
what drug is given for agitation, but can actually increase agitation in some?
Why is this?
benzos
work on PFC and decrease self control
what is a long-term treatment for aggression in dementia?
SGA
what is the short-term treatment for panic attacks?
benzos
what is the longest amount of time you should put a person on benzos for?
4 weeks — addicting d/t dopamine surge!!
what are two long-term therapy options for panic disorder?
SSRIs
SNRIs