Pharm

Question 1

ALPHA 1 RECEPTOR

Tissues - Actions (3)

Answer 1

“Gimme an alpha 1 VID”

(1) Most Vascular smooth muscle- contracts (inc. vascular resistance)
(2) Dilator Pupillary muscle- contracts (myDriasis)
(3) Internal Urethral Sphincter- contracts

Question 2

ALPHA 2 RECEPTOR

Tissues- Actions (5)

Answer 2

“You’ll find alpha 2 receptors on a PPEAA”

(1) [Adrenergic and cholinergic nerve terminals]- inhibits NTS release–> [CNS-mediated BP DEC]
(2) Platelets- stimulates aggregation
(3) Pancreas- DECREASES Insulin Release
(3) Adipocytes - DEC Lipolysis
(4) Eye - DEC Intraocular pressure

Question 3

BETA 1 RECEPTOR

Actions (2)

Answer 3

(1) Heart- INC rate and force by [INC [Na+ I(f) channels] in phase 0 of AV node] –> shortens PR interval
(2) JGA cells- Stimulates renin release

Question 4

BETA 2 RECEPTOR

Tissues-Actions (4)

Answer 4

“B Team Team 2 Rarely Loves Play Time”

(1) Relaxes RUV - (Respiratory, Uterine and Vascular) smooth muscle
(2) Liver- stimulates glycoGenolysis
(3) Pancreatic B cells- stimulates insulin release
(4) Tremor activation by @ [voluntary m. somatic n. terminals]

Question 5

BETA 3 RECEPTOR Tissues-Actions

Answer 5

Fat cells- stimulates Lipolysis

(B1 and B2 may also contribute)

Question 6

DOPAMINE 1 RECEPTOR

Tissues-Actions

Answer 6

Renal and other splanchnic blood vessels- vasoDilates (reduces resistance)

D for Dopamine Receptor

Question 7

DOPAMINE 2 RECEPTOR

Tissues-Actions

Answer 7

Nerve terminals- inhibits adenylyl cyclase

Question 8

What target organ does the M1 Receptor work in

Answer 8

“[M1s need Brain], [M2s need Heart], [M3s BEGs for Private Lounges”

Brain

Question 9

What target organ does the M2 Receptor work in

Answer 9

“[M1s need Brain], [M2s need Heart], [M3s BEGs for Private Lounges”

Heart

Question 10

What target organ does the M3 Receptor work in (6)

Answer 10

“[M1s need Brain], [M2s need Heart], [M3s BEGs for Private Lounges”

“M3’s BEGS for Private Lounges”

Bladder(contraction) / Eyes / GI / Skin / [Peripheral Vasculature] / Lungs