Pharm Flashcards
1
Q
A 44-year-old Bangladeshi man with a history of mitral stenosis and atrial fibrillation is diagnosed with tuberculosis. He is commenced on anti-tuberculosis therapy. Three weeks after starting treatment his INR has increased to 5.6. Which one of the following medications is most likely to be responsible for this increase?
A
Isoniazid
Isoniazid inhibits the P450 system