Pharm Flashcards

1
Q

A 44-year-old Bangladeshi man with a history of mitral stenosis and atrial fibrillation is diagnosed with tuberculosis. He is commenced on anti-tuberculosis therapy. Three weeks after starting treatment his INR has increased to 5.6. Which one of the following medications is most likely to be responsible for this increase?

A

Isoniazid

Isoniazid inhibits the P450 system

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