Pharm Flashcards

1
Q

What is a peak

A

Highest level of med- taken after med is given

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2
Q

Who prepares TPN?

A

Pharmacy

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3
Q

What should be monitored with TPN and why?

A

Glucose- high glucose can have an osmotic diuresis effect on the body

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4
Q

What med can cause tendon rupture?

A

Cipro

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5
Q

What tendon is most likely affected in tendon rupture

A

Achilles’ tendon

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6
Q

When can tendon rupture occur when a pt is admin Cipro?

A

As much as 8-12 weeks after the med is stopped

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7
Q

What does potassium sparing mean ?

A

Inhibits the excretion of potassium from the tubules and therefore keeps potassium in the body

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8
Q

Potassium sparing diuretics are often used with which 2 types of drugs

A

Loop diuretics

Thiazides

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9
Q

Name 2 potassium sparing diuretics

A

Lasix

Aldactone

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10
Q

What is positive inotrope

A

Increases pumping action of the heart

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11
Q

What is negative inotrope

A

Decreases force of contraction of the heart

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12
Q

If a pt gets a headaches from the admin of nitro, should you stop the med?

A

No - continue tx

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13
Q

Which insulin gets drawn first - reg or nph?

A

Regular

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14
Q

When mixing insulin, what is the rule

A

Clear— cloudy

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15
Q

When DM pt getting contrast dye, what medication should be held

A

Metformin

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16
Q

Why should metformin be held when a DM pt is going through dye contrast studies

A

Can cause lactic acidosis and renal impairment

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17
Q

When should metformin be held when a DM pt is undergoing contrast studies

A

Pre and post contrast studies

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18
Q

When should thyroid meds be taken

A

Same time each day

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19
Q

Should thyroid meds be taken before or after eating

A

Before eating- on an empty stomach

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20
Q

What is PTU caused by

A

Overacting thyroid

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21
Q

What increases the absorption of iron in the body

A

Vit c

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22
Q

What decreases the absorption of iron in the body

A

Calcium

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23
Q

What is the difference bx anticoagulant and anti-platelets

A

Anticoagulants interfere with clotting process

Antiplatelets interfere with plt aggregation

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24
Q

Name some examples of anti-plt

A

ASA

Plavix

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25
What routes is heparin administered
IV | SQ
26
Onset of heparin effectiveness
Immediate
27
What labs should be done when heparin is admin
Ptt/ aptt
28
What is a heparin antidote
Protamine sulfate
29
What should the ptt/ aptt values be with heparin
35-80
30
What is the normal aptt?
30- 40 secs
31
If the _____ lab value is ______, we admin protamine sulfate for the antidote to heparin
``` Aptt Too high (above 80) ```
32
What is a normal INR levels with no coats?
1-2
33
What routes is warfarin admin
Po | IV (rare)
34
How long does it take warfarin to be effective after being admin the first dose
3- 5 days
35
What labs are drawn when pts are taking warfarin
INR
36
What is the antidote for warfarin
Vit k
37
What should the INR be at a therapeutic level with Coumadin
2-3 | 2.5-3.5 with an artificial valve
38
Thrombolytics must be admin by what time frame after a clot/ cva
4-5 hours
39
Ppl with ________ _____________ have a fit b-12 deficiency
Pernicious anemia
40
How is vit b-12 admin and why
Injected | Ppl w/ pernicious anemia do not make the subs in the stomach to absorb/ break down b12
41
Antacids should be admin how long after iron admin
60 mins
42
What are some common s/e's of diuretics
Hypokalemia Hyponatremia Hyperglycemia
43
When taking k sparing diuretics, what dietary item should be avoided
Salt substitutes
44
What abx are known to be nephro and ototoxic
Gentamicin | Vancomycin
45
What abx can cause red mans syndrome
Vanco
46
How can red mans syndrome be avoided
Vanco must be admin over an hour
47
What s/s will be seen with red mans syndrome
Decreased bp | Flushed look
48
Methotrexate lowers what lab values
Wbc's Plts RBC's
49
What should be monitored with methotrexate
Infec
50
Plaque nil is known for causing _________ damage
Retinal
51
Pts with gout should avoid which dietary foods
Purines- -organ meats Gravies Sardines
52
What 2 meds are normally given to ppl with gout
1- zyloprim- long term maintenance | 2- colchicine - flare up
53
When a pt is on NSAIDs, what should be monitored
Bleeding
54
What suffixes are assoc with psych meds
Lam | Pam
55
When pts are taking MAOI's, they should avoid what?
Tyramine
56
What can happen if a pt ingests tyramine when taking MAOI's
Hypertensive crisis
57
A-typical anti-psychotics are known to cause what
Agranulocytosis
58
What should be monitored with patients on a-typical antipsychotics
CBC - WBC count
59
Haldol is a ________ anti-psychotic
Typical
60
Common adverse Rxns of haldol
TD | EPS
61
Lithium is a med given for
Bipolar
62
Lithium toxicity increases with what condition and how can it be Prevented
Hyponatremia | - maintain adequate Na and hydration
63
What medication can cause lithium toxicity
NSAIDs
64
What is the ther lithium level
0.4-1.4
65
Parkinson's meds are C/I with what med and condition
MAOI's, benztropine (cogentin) | Narrow angle glaucoma
66
What is the time frame for emergency contraception
Must be taken within 72 hrs
67
What is the antidote for mg
Calcium gluconate
68
What does magnesium tox look like
*** decr DTR's *** Decr urine output Low BP Decr RR
69
S/s lactic acidosis
Change in LOC Myalgia Malaise Hyperventilation
70
What med may be given for PP bleeding
Methergine
71
Methergine is C/I in what condition
HTN
72
What risks can cause PP hemorrhage
Overstretching Overusing Multiples
73
What 2 reasons is pitocin used for
Induce/ augment labor | PP hemorrhage
74
What is the main s/e of pitocin
Incr BP
75
What is the purpose of tocolytics
Relax uterus
76
Name 2 tocolytics
Terbutaline | Mg
77
Pts on protonix are at an increased risk for what and why?
PNA | Decreases the acid that would have killed upper respiratory bacteria
78
What drug class is risperidone
A-typical antipsychotic
79
What conditions is risperidone used for
Schiz BPD Autism
80
Pts taking symbicort are at risk for _____ and why?
Oral candidiasis- PO steroids
81
When should synthroid be taken and why
In the morning | Causes insomnia
82
When is a trough level drawn
15 mins before dose admin
83
When is a peak level drawn?
30 mins after dose is admin
84
The meningitis covers how many strains of meningitis
4
85
What meds cause ototoxicity in high doses
Lasix Gentamycin Aspirin
86
Can it's who are allergic to pcn take cephalosporins and a possible reason why?
No | Cross sensitivity
87
What are the most common cephalosporins
Keflex | C-core
88
What is the most common quinolone
Cipro
89
Other than bacterial infects, what is Cipro used or ?
STD's | Anthrax
90
What is the most common macrolide
Azithromides (z-pack)
91
What are macrolide so used to treat
Resp infection
92
What is used to treat Lyme disease
Doxycycline
93
Who is at most risk for c-diff
Pt in a hospital on an IV abx
94
What is the first drug of choice for seizures
Keppra
95
What is the old drug used for seizures
Dilantin
96
What are common ED meds
Levitra Viagra Cialis
97
Iron antidote
Deferoxamine
98
What are PRBC's admin for ?
Severe anemia
99
How is amount of PRBC's to admin adequately dosed?
Each unit of PRBC's will increase RBC's by 1 g/ dL
100
What is admin for burns
FFP
101
What should be monitored in burn victims
Albumin
102
What is the normal albumin range
3.5- 5
103
What is admin for hemophilia
Cryoprecipitate factor VIII
104
What do you monitor for when admin a hemophiliac cryoprecipitate factor VIII ?
PTT
105
What is the normal PTT range
30-40
106
What is the ther PTT range
45-80
107
S/s of benzo wd
Tachycardia Hand tremors Seizures
108
What is an example of benzo
Xanax
109
What is a trough
Lowest level - usually taken before med is given