Pharm Flashcards

0
Q

Venodilation

A

Nitrates

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1
Q

Octreotide

A

Acromegaly
VIPoma
Variceal bleed
Carcinoid

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2
Q

Moa nitrates

A
Myosin light chain de phosphorylation 
Increase cGMP (NO) 
Decrease intra cellular calcium
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3
Q

HY side effects nitrates

A

Headache
Flushing
Monday disease– loss tolerance

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4
Q

What to give with a nitrate ?

A

Beta blocker (since tachycardia and hypotension)

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5
Q

Cyanide toxicity with which drug?

A

Nitroprusside

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6
Q

Use Nitroprusside?

A

Hypertensive crisis

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7
Q

Decrease preload and after load

A

ACE inhibitors
ARBs
Nitroprusside
Nesiritide

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8
Q

Antidote Nitroprusside

A

Sulfur

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9
Q

Nesiritide

A

Bnp recombinant

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10
Q

Moa Nesiritide

A

Increase cGMP
Arteriolar and venous vasodilation
Natriuresis

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11
Q

Hydralazine

A

Arteriolar vasodilation
Increase K perm
Inhibit sarcoplasmic calcium

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12
Q

Reflex tachycardia

Fluid retention

A

Hydralazine side effects

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13
Q

Two things give with Hydralazine

A

Beta blocker

Diuretic

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