PH, PKa, Biological Buffering- Keagan Flashcards
1
Q
Acid v base on protons
A
Acid- release proton
Base- accept proton
2
Q
pH formula
A
pH= -log10[H+]
3
Q
Factor of 10 difference in [H+]= __ pH unit
A
1.0 pH
4
Q
Factor difference of 2 [H+]= __ pH
A
= 0.3 pH
5
Q
Henderson- hasselbalch equation
A
pH= pKa + log ([A-]/ [HA])
PKa= -log Ka
Ka= [H+] [A-]/ [HA]
6
Q
pH < PKa =
A
Protonated
7
Q
pH > PKa=
A
Deprotonated
8
Q
Respiratory acidocis
A
Decreased ventilation and increased Pco2
(Pco2> 40 mmHg/ HCO3- >24 mM)
After partial renal compensation
9
Q
Metabolic acidocis
A
Decreased extracellular fluid HCO3-
HCO3- < 24mM
Pco2 <40 mmHg
After partial respiratory compensation
10
Q
Respiratory alkalosis
A
Increased ventilation and decreased Pco2
Pco2<40mmHg
HCO3-< 24mM
After partial renal compensation
11
Q
Metabolic alkalosis
A
Increased extracellular HCO3-
HCO3- >24mM
Pco2> 40 mmHg
