Pgp Flashcards
Rifampin
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
St. Johns Wart
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
Carbamazepine
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
Phenytoin
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
Ritonavir
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
efavirenz
[Inducer/Inhibitor/Substrate] of Pgp
Inducer
quinidine
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Verapamil
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Amiodarone
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Clarithromycin
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
erythromycin
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Itraconazole
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Rifampin
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
Digoxin
[Inducer/Inhibitor/Substrate] of Pgp
Substrate
Ritonavir
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
T/F
Rifampin has dual effects depending on dosing regimen
True
Both an inducer & inhibitor
T/F
Ritonavir has dual effects depending on dosing regimen
True
Both an inducer & inhibitor
These three cardiac drugs were listed as pgp inhibitors
- quinidine
- Verapamil
- amiodarone
These three antimicrobials were listed as pgp inhibitors
- Clarithromycin
- azithromycin
- itraconazole
Azithromycin
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor
HIV regimens containing this agent are recognized as pgp inhibitors
Ritonavir
This immunosuppressant is a pgp inhibitor
Cyclosporine
Cyclosporine
[Inducer/Inhibitor/Substrate] of Pgp
inhibitor
These two drugs are inducers or inhibitors of pgp depending on their regimen
- Rifampin
2. Ritonavir
Atorvastatin
[Inducer/Inhibitor/Substrate] of Pgp
Inhibitor