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PCEUT 510 > Pgp > Flashcards

Pgp Flashcards

1
Q

Rifampin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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2
Q

St. Johns Wart

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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3
Q

Carbamazepine

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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4
Q

Phenytoin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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5
Q

Ritonavir

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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6
Q

efavirenz

[Inducer/Inhibitor/Substrate] of Pgp

A

Inducer

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7
Q

quinidine

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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8
Q

Verapamil

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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9
Q

Amiodarone

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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10
Q

Clarithromycin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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11
Q

erythromycin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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12
Q

Itraconazole

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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13
Q

Rifampin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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14
Q

Digoxin

[Inducer/Inhibitor/Substrate] of Pgp

A

Substrate

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15
Q

Ritonavir

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

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16
Q

T/F

Rifampin has dual effects depending on dosing regimen

A

True

Both an inducer & inhibitor

17
Q

T/F

Ritonavir has dual effects depending on dosing regimen

A

True

Both an inducer & inhibitor

18
Q

These three cardiac drugs were listed as pgp inhibitors

A
  1. quinidine
  2. Verapamil
  3. amiodarone
19
Q

These three antimicrobials were listed as pgp inhibitors

A
  1. Clarithromycin
  2. azithromycin
  3. itraconazole
20
Q

Azithromycin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

21
Q

HIV regimens containing this agent are recognized as pgp inhibitors

A

Ritonavir

22
Q

This immunosuppressant is a pgp inhibitor

A

Cyclosporine

23
Q

Cyclosporine

[Inducer/Inhibitor/Substrate] of Pgp

A

inhibitor

24
Q

These two drugs are inducers or inhibitors of pgp depending on their regimen

A
  1. Rifampin

2. Ritonavir

25
Q

Atorvastatin

[Inducer/Inhibitor/Substrate] of Pgp

A

Inhibitor

PCEUT 510 (12 decks)

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