PET/CT GENERAL Flashcards

1
Q

Noncolinearity

A

positron and negatron particles are in motion at the time of interaction, and their momentum causes a slight deviation in the angle of their flight path. Results in a 2mm blurrring effect.

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2
Q

Disintegration’s per minute formula?

A

cpm / % efficiency

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3
Q

MLEM

A

Maximum Likelihood Expectation Maximization -

Iterative reconstruction

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4
Q

OSEM

A

Ordered Subset Expectation Maximization-

Iterative Reconstruction

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5
Q

AWOSEM

A

Attenuation Corrected OSEM

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6
Q

RAMLA

A

Row Action Maximization Likelihood Algorithm

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7
Q

GTV - Gross Tumor Volume

A

Extent of tumor growth

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8
Q

CTV - Clinical Tumor Volume

A

GTV + microscopic disease in surrounding tissue

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9
Q

PTV - Planning Tumor Volume

A

Needed beam volume to cover CTV

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10
Q

Bremsstrahlung Radiation

A

Loss of kinetic energy and deviation of the electron path. Continuous spectrum of x-rays. Reduction of low energy x-rays by window of the x-ray tube

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11
Q

kVp

A

tissue penetration

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12
Q

mA

A

noise

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13
Q

Increment

A

determines the degree of overlap between successive images

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14
Q

Beam Hardening Artifact

A

Streak artifacts occurs when x-ray photons of low energy create an increase in the x-ray energy at the center of the object.

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15
Q

Rigid Registration

A

relies on anatomic landmarks (may be operator or auto selected)

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16
Q

Deformable registration

A

allows deformation due to body position, tissue or organ position changes. May apply a regional mutual information technique.

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17
Q

Image Segmentation

A

Areas of similar tissue, replaces pixel values with known values.

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18
Q

Frontal Lobe

A

Cognition, motor function

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19
Q

Parietal Lobe

A

Sensory function, memory

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20
Q

Temporal Lobe

A

Memory, speech recognition

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21
Q

Occipital Lobe

A

Vision

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22
Q

Brain Stem and Cerebellum

A

Basic life functions, balance

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23
Q

Dementia

A

Decline in cognitive function beyond what is expected based on age alone

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24
Q

C11 Half-Life

A

20.3 minutes

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25
Q

N13 Half-Life

A

9.97 minutes

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26
Q

O15 half-life

A

2.03 minutes

27
Q

F18 half-life

A

110 minutes

28
Q

Rb82 half-life

A

75 seconds

29
Q

Sr82 half life

A

25 days

30
Q

Sr82 generator tested for

A

Sr82 and Sr85 contaminates <0.02uCi

31
Q

Deuterons

A

Proton plus a neutron

32
Q

Neutrophilic Substitution

A

a chemical reaction in which an electron-rich group of atoms changes place on a molecule with a positively charged “leaving group” of atoms.

33
Q

Dose Calculation by weight

A

kg x 0.14mCi / kg

34
Q

Most common tech for processing 3d sonograms?

A

FORE (Fourier Rebinning)

35
Q

What does breathing artifact look like on fuse image

A

photopenic areas located in the area of the diaphragm.

36
Q

Truncation

A

Occurs when the patient’s body or extremities exceeds the 50cm fov, but is imaged in the 70cm fov pet.

37
Q

Absolute Activity Calibration (Well Counter)

A

Calibration information to convert counts/voxel into absolute activity

38
Q

SUV formula

A

SUV = measured act / volume x pt weight / injected act

39
Q

mBq =

A

37 x mCi

40
Q

max exposure for preg tech

A

500 mRem

41
Q

Inverse square law

A

I1D1(2) = I2D2 (2)

42
Q

10 CFR 20 limits exposure to?

A

100mR/yr and 2mR/hr and < 0.05mR/hr for staff

43
Q

Which contrast agent breaks down in blood stream

A

Ionic

44
Q

Which contrast agent does not break down in bloodstream

A

Non-Ionic

45
Q

Myocardium with contractile dysfunction despite normalization of perfusion

A

Stunned Myocardium

46
Q

Defect at rest, still viable

A

Hibernating Myocardium

47
Q

Term used to identify atoms with excessive thermal or kinetic energy or electronic excitation.

A

Hot atom

48
Q

Serotonin System controls what

A

disorders such as anxiety, depression, sleep disorders, eating disorders, and violence

49
Q

Dopamine System controls what

A

regulation of movement, motivation, and cognition

50
Q

Deficiency in cholinergic activity is

A

Alzheimer Disease

51
Q

The kinetic energy of the annihilation is shared bettween the

A

electron and neutrino

52
Q

Agent used most commonly for tumor response

A

C11 - Methionine

53
Q

Agents for Cellular ProliferationAgen

A

C11 Thymidine and F18 Fluorothymidine

54
Q

Agent for Neuroendocrine tumors

A

F18-DOPA

55
Q

Agents used for Hypoxia Imaging

A

F18 FMISO and Cu-ATSM

56
Q

Agent for Cerebral Blood Flow (rCBF)

A

O15-labeled carbon dioxide.

57
Q

Agents used for Myocardial Perfusion

A

N13 ammonia and Rb82

58
Q

Rb82 works because its a

A

Potassium analogue

59
Q

N13 ammonia works because its a

A

passive diffusion and retained by the amino acid pool as glutamine

60
Q

Assessment of myocardial oxygen consumption is done with

A

C11-Acetate

61
Q

normal pT level

A

11-13 seconds

62
Q

normal pTT level

A

30-50 seconds

63
Q

normal platelet count

A

150k - 400k