PET CT Flashcards
pet radiotracer positron interaction?
positron and electron will meet, annihilate and create 2 511 keV photons traveling 180 degrees apart
how are photons detected on PET CT?
circular crystal
F18 half life?
110 min
F18 FDG
F-18-fluorodeoxyglucose (F-18 FDG); glucose analog competing for transport into GLUT 1/3 trasnporters
FDG is phosphorylated by hexokinase and is trapped into cells
what is SUV?
standardized uptake value; proportional to ROI activity x body weight/administered activity
how does SUV change
equipment, time elapsed since FDG administered, amount of tracer extrav, muscle uptake, glucose, insulin levels at time of injection
NPO time for PET
4 hrs for insulin to reach basal level; glucose < 1500 (200 upper limit)
normal FDG uptake
brain, KUB, glands, liver, bowel, heart, muscle, brown fat
smallest nodule that can be reliably evaluated by PET
8mm suspicious pulmonary nodule
pulmonary nodules that may not be FDG avid
bronchioalveolar cell carcinoma or carcinoid
how long to delay PET CT after colon cancer treatment?
2 months due to flare phenomenon
how long to delay PET CT after H&N cancer treatment?
delay 4 months after treatment
thyroid FDG avid?
undifferentiated or medullary thyroid cancer