Pernicious Anaemia

Question 1

macrocytic anaemia and neuropathic pain are concerning for

Answer 1

underlying B12 deficiency/pernicious anaemia

Question 2

investigating vitamin B12 deficienc

Answer 2

Intrinsic factor antibodies

Intrinsic factor antibodies are more useful than gastric parietal cell antibodies when investigating vitamin B12 deficiency, given low specificity of gastric parietal cell antibodies