Peritonitis Flashcards
What is the MOST common classification of peritonitis?
Secondary generalized septic peritonitis
What is the MOST common etiology for peritonitis?
a. GI tract
b. urogenital
c. hepatobiliary system
d. penetrating foreign bodies
a. GI tract
followed by urogenital
Peritonitis occurs as a result of an initial injury which leads to inflammation, vascular permeability, and fluid leakage.
What causes the mast cells degranulation and cytokine release that leads to further inflammation and and leakage and can cause severe changes such as hypovolemia, fibrin, shock, SIRS and DIC?
the immune reaction to the fluid that leaked.
What are some things in the history that may make you more suspicious that peritonitis is occurring when you are seeing appropriate clinical signs?
Recent abdominal surgery or FB (dehiscence)
being on steroids/NSAIDs (ulcers)
any trauma (HBC, BDLD)
or being intact (pyo)
The following are non-specific clinical signs you may see for WHAT surgical disease?
- abdominal pain
- fluid wave
- abdominal distension
- fever
- anorexia
- vomiting & diarrhea
- lethargy
peritonitis
A patient presents to your ER clinic as a referral from a local GP. This patient is tachycardic, has pale MM, and is severely dehydrated. You take the blood pressure and it reads 30. What is likely occuring in this patient?
shock! most likely hypovolemic shock.
What diagnostics can you run to diagnose peritonitis?
- CBC/Chem with electrolytes
- PT/PTT
- Abdominocentesis (cytology, culture, and lactate)*
A patient presents to you and is having non-specific signs associated with peritonitis. You run a CBC/Chem/Electrolytes on this patient. The results show what for the following categories:
- WBCs:
- RBCs:
- Protein:
- Glucose:
- Electrolytes:
- Kidney values:
- Liver values:
- WBCs: marked toxic neutrophilia
- RBCs: anemia
- Protein: hypoproteinemia
- Glucose: hyper or hypoglycemia
- Electrolytes: low Na, Cl, K
- Kidney values: azotemia
- Liver values: enzyme elevation
A patient presents to you and is having non-specific signs associated with peritonitis. You run a PT/PTT on this patient. The results show what?
If in DIC, then times will be prolonged. This has a poorer prognosis and should be corrected with an albumin transfusion.
A patient presents to you and is having non-specific signs associated with peritonitis. You perform abdominocentesis on this patient to look at a cytology of the fluid. What could you possibly see?
- degenerative neutrophils
- intracellular bacteria
- vegetative material
- bile
- neoplastic cells
What is characteristic of peritonitis on abdominal radiographs?
loss of serosal detail
gas behind the diaphragm
T/F: the prognosis of peritonitis depends on the inciting cause
true
What are the 7 negative prognostic factors for peritonitis?
- refractory hypotension
- cardiovascular collapse
- respiratory distress
- disseminated intravascular coagulation
- plasma lactate > 2.5 mmol/L
- ionized hypocalcemia
- multiple organ dysfunction syndrome
In general, how do you approach treating a patient with peritonitis?
- stabilize them
- administer appropriate antibiotics
- control and fix the problem via exploratory laparotomy
- lavage & drain abdominal cavity
- consider placing a feeding tube
What pre-operative drugs should you not use in peritonitis cases?
NSAIDs to spare the GI tract and the kidneys