peripheral vascular disease Flashcards

1
Q

what are the complications of plaques?

A
  • stenosis - plaque increases in size - either moves outwards or inwards blocking the lumen
  • stenosis progresses to occlusion
  • haemorrhage
  • plaque rupture
  • overlying thrombosis and embolism
  • dissection
  • aneurysm
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2
Q

which parts of the body are most likely to get atherosclerosis?

A

the parts furthest away from the heart

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3
Q

what are the symptoms of critical leg ischaemia?

A

pain at REST
ulceration
gangrene
(only need one of these for diagnosis)

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4
Q

what are the SIGNS of acute limb ischaemia?

A
pale 
pain 
paralysis 
paraesthesia
perishing cold 
pulseless
don't need all of these, depends on how acute and severe the ischaemia is
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5
Q

what are the different types of peripheral vascular disease?

A
intermittent claudication 
critical leg ischaemia 
acute limb ischaemia 
carotid artery disease eg stroke, TIA, amaurosis fugax
abdominal aortic aneurysm
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6
Q

what is intermittent claudication?

A

moderate ischaemia
pain in the large muscles of the leg as oxygen demand exceeds supply
this causes lactic acid to form which accumulates and leads to pain
pain on exertion
pain distal to the site of atheroma (as this is the area that is getting cut off)
classically affects the calf muscles
resolves on resting

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7
Q

what is critical leg ischaemia?

A

the blood supply to the lower limb is insufficient for basal metabolism ie too low to sustain life
commonly happens at night when the HR and resp rate are reduced and wakes people from sleep
the leg is red as it is massively vasodilated to increase blood supply
risk of infarction and infection

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8
Q

How do we treat peripheral vascular disease?

A

risk factor modification for atherosclerosis

revascularisation after having done a risk benefit analysis

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9
Q

what are the components of risk factor modification for treatment of peripheral vascular disease?

A
exercise and weight reduction 
reduce hypertension
reduce hyperlipidaemia
diabetes 
antiplatelet therapy
smoking cessation
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10
Q

What interventions can be done for peripheral vascular disease?

A
femorodistal vein bypass
percutaneous balloon angioplasty
amputation 
carotid endarterectomy
open aneurysm repair
endovascular repair of aneurysm
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