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First year > Peripheral Neuropathy > Flashcards

Peripheral Neuropathy Flashcards

1
Q

Presents shortly after infection

A

Guillian-Barre Syndrome

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2
Q

Guillain-Barre Syndrome is caused by?

A

Antibodies against own schwann cells

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3
Q

Treatment for Guillaine-Barre

A

Admit, Monitor, Intravenous Ig

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4
Q

Is Guillain-Barre an Axonopathy or a Myelinopathy

A

Acute Myelinopathy

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5
Q

Features of Diabetic Neuropathy

A

Glove and Stocking - PolyneuropathyAxonalChronic

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6
Q

Features of Toxic Neuropathy

A

PolyneuropathyChronicAxonal Degeneration

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7
Q

What is Lambert Eaton Myasthenic Syndrome (LENS)

A

Antibodies against voltage-gated Ca channels

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8
Q

Features of Lambert Eaton Myasthenic Syndrome

A

Fatiguable limb weaknessesAbsent reflexesAutonomic features

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9
Q

What is Myasthenia Gravis

A

Aquired autoimmune disease.Antibodies against Nicotinic ACh receptors

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10
Q

Features of Myasthenia Gravis

A

Fatiguable weaknessDouble VisionDrooping EyelidsDysphagia

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11
Q

Treatment for Myasthenia Gravis

A

Anticholinesterase DrugsIntravenous Ig

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12
Q

What types of Acetylcholine Receptors are there.

A

NicotinicMuscarinic

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13
Q

Features of Nicotinic ACh receptors

A

Ligand-gated Ionotropic (Ion channels)Afinity to Nicotine

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14
Q

Features of Muscarinic ACh receptors

A

Metabotropic (Not a channel)Afinity to Muscarine

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15
Q

What neurotransmitters effect Adrenergic receptors

A

Norepinephrine (Noradrenaline)Epinephrine (Adrenaline)

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16
Q

Where are alpha-1a,b,c subtype of Adrenergic receptors located

A

Vascular smooth muscleHeart

17
Q

Agonist and Antagonist for alpha-1a,b,c Adrenergic receptors and their effects

A

Agonist - Methoxamine (Hypotension - Raise BP)Antagonist - Doxazosin (Hypertension - Lower BP)

18
Q

Where are alpha-2a,b,c subtypes of Adrenergic receptor located

A

CNSPlateletsNerve Terminals

19
Q

Agonist and Antagonist for alpha-2a,b,c Adrenergic receptors and their effects

A

Agonist - Guanfacine (Hypertension - Lower BP)Antagonist - Yohimbine

20
Q

Name the 3 types of Beta Receptors and their locations

A

B1 - HeartB2 - Respiratory, Uterine, SkeletalB3 - Fat Cells

21
Q

Examples and actions of B Agonist and Antagonist

A

Agonist Isoproterol (Increase HR, Cardiac Output) Salbutamol - AsthmaAntagonist - Propranolol (Decrease HR, Cardiac Output) Bisoprolol Timolol - Glaucoma Treatment

First year (11 decks)

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