Peripheral Nerve Blocks Flashcards
What determines our choice of anesthetic? (5)
time to onset
duration of action
degree of sensory block to motor block
risk of cardiac toxicity
how many areas need to be blocked
What is the dose and duration of bupivacaine?
3mg/kg
1.5 - 8 hours
What is the dose and duration of lidocaine?
- 5 mg/kg, 7 with epi
- 75 - 2 hours
What is the dose and duration of mepivicaine?
4.5 mg/kg, 7 with epi
1-2 hours
What is the dose and duration of ropivacaine?
3 mg/kg
1.5-8 hours
Name the amides: (5)
bupivacaine
lidocaine
mepivacaine
prilocaine (used for dental, PNB)
ropivacaine
Name the esters: (5)
benzocaine
chloroprocaine
cocaine
procaine
tetracaine
What are the concentrations of bupivicaine?
- 25%
- 5%
- 75%
What are the concentrations of lidocaine?
0.5-5%
What are the concentrations of mepivacaine?
1-3.5% in 0.5% increments
What are the concentrations of ropivacaine?
0.2, 0.5, 0.75, 1%
What is the max dose and duration of chloroprocaine?
12 mg/kg
All esters are 0.5 - 1 hr except tetracaine.
What is the max dose and duration of cocaine?
3mg/kg
All esters are 0.5 - 1 hr except tetracaine.
What is the max dose and duration of tetracaine?
3mg/kg
1.5-6 hours
What is the max dose and duration of procaine?
12 mg/kg
0.5-1 hr
Why do we use epinephrine? (4)
Intravascular marker: increase HR by 20%
Improves quality of block: increased neuronal uptake, and alpha2- adrenergic receptors
Decreases absorption: prolong action
Vasoconstriction on surgical field
What amount of epinephrine do we add to LA?
5 mcg/ml (1:200,000)
2.5 mcg/ml (1:400,000)
What are the major risks of nerve blocks?
Systemic toxicity, rare but fatal
Infection
Peripheral nerve damage
Note: Use B bevel needles (short bevel) to reduce risk of nerve damage.
What vascular areas are most to least prone to systemic toxicity? (8)
Tracheal
Intercostal
Caudal
Paracervical
Epidural
Brachial plexus
Sciatic
subcutaneous
What are the signs and symptoms of CNS excitation toxicity? (6)
Dizziness
Tinnitis
Circumoral numbness
Muscle twitches
Slurred speech
Seizures
What are the cardiovascular signs of toxicity? (5)
Depress myocardial conduction and contractility
Produce arterial vasodilatation, except cocaine
Hypotension
Bradycardia, PVCs, PACs
VT or VF
How do you prevent systemic toxicity?
Incremental injection
Frequent aspiration
Adding a marker
Limiting LA dose and concentration
Continual communication with patient
In a nerve block, proceed with caution in what patients?
Patients with cardiac conduction abnormalities
Kidney or liver disease
Acidosis
How do you treat seizures from systemic toxicity?
midazolam, propofol, thiopental







