Peripheral Arterial Disease Flashcards
What is Peripheral Arterial Disease?
Narrowing of the arteries supplying the limbs and periphery, reducing blood supply
Leads to symptoms of claudication
What are the symptoms of claudication?
Pain
Cramping
Parasthesia
What is intermittent claudication?
Symptom of ischaemia in a limb
When does intermittent claudication occur?
During exertion
Relieved by rest
What is experienced in intermittent claudication?
Crampy, achy pain in the calf, thigh or buttocks
Associated with muscle fatigue when walking
What is critical limb ischaemia?
End-stage of peripheral arterial disease
Inadequate supply of blood to a limb at rest
What are the features of critical limb ischaemia?
Pain at rest
Non-healing ulcers
Gangrene
SIGNIFICANT RISK OF LIMB LOSS
What is acute limb ischaemia?
Rapid onset of ischaemia in a limb
Why does acute limb ischaemia occur?
Thrombus blocks the arterial supply to the distal limb
What is ischaemia?
Inadequate oxygen supply to the tissues due to reduced blood supply
What is necrosis?
Death of tissue
What is gangrene?
Death of the tissue due to inadequate blood supply
What is atherosclerosis?
Atheromas (deposits in the artery walls) harden causing stiffening of the blood vessels
What vessels are affected by atherosclerosis?
Medium and large arteries
What causes atherosclerosis?
Caused by chronic inflammation and activation of the immune system in the artery walll