peripheral arterial disease Flashcards

1
Q

what are the 3 types of PAD?

A
  1. intermittent claudication:
    - inadequate increase in muscle perfusion during exercise
  2. critical limb ischaemia
    - advanced form of chronic ischaemia, symptoms include night pain
  3. acute limb ischaemia
    - caused by emboli
    - tend to lodge at artery bifurcations
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2
Q

what are the risk factors for PAD?

A
  • Smoking is the greatest risk factor
  • advancing age
  • hypertension
  • hypercholesterolaemia
  • heart disease (AF) for acute limb ischaemia
  • CKD
  • high serum homocystine- increases when eat meat
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3
Q

what is the name of the classification system for PAD?

A

Fontaine classificiation

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4
Q

why may PAD appear to be asymptomatic, and what might you see on examination of these patients?

A

Symptoms may be masked by an inability to walk (e.g. severe heart failure) or due to pain insensitivity (e.g. diabetic neuropathy)

on examination:
Low ABPI (<0.90) or lack of palpable pulse
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5
Q

what are the different stages of PAD according to fontaine classification?

A

stage 1: asymptomatic

stage 2: intermittent claudication which is not present at rest.
2a-> happens after walking more than 200m
2b-> happens after walking less than 200m

stage 3: critical limb ischaemia

  • pain present at rest
  • dangling leg over bed at night can help pain
  • imminent risk of limb loss

stage 4: tissue loss, ulceration and gangrene

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6
Q

where is the underlying pathology if person presents with unilateral buttock pain?

A

common illiac

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7
Q

where is the underlying pathology if person presents with unilateral thigh pain?

A

common femoral

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8
Q

where is the underlying pathology if person presents with unilateral calf pain?

A

superficial femoral

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9
Q

what is it called when you have the triad of ….
Bilateral buttock and thigh claudication
Absent or decreased femoral pulses
Erectile dysfunction

A

Aortoiliac (Leriche syndrome)

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10
Q

what is the appearance of an arterial ulcer?

A

Site: lower legs and tops of feet or toes
Symmetrical shape, well-defined borders, ‘punched-out appearance’
Painful, particularly at night
Minimal bleeding when touched or knocked

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11
Q

what is the primary investigation for peripheral arterial disease?

A

Ankle-brachial pressure index (ABPI)

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12
Q

what does ABPI >1.3 suggest?

A

Abnormally calcified vessels; false-negative often due to diabetes. Any value >1.5 should not be used to guide decision making

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13
Q

which ABPI values are considered normal?

A

0.8-1.3

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14
Q

what value ABPI will someone with intermittent claudication likely have?

A

0.5-0.79

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15
Q

what does an ABPI value <0.5 suggest?

A

Severe arterial disease; rest pain, ulceration, gangrene (critical limb ischaemia)

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16
Q

what investigative results would raise suspicion of acute limb ischaemia?

A

Absence of pulse in the lower extremity on doppler ultrasound; ABPI cannot be calculated

17
Q

what is the first line imaging offered to investigate PAD?

A

Duplex ultrasound: first-line imaging, offering some information on the location and severity of stenosis. It is also the method of choice for routine follow-up after revascularisation to assess vein quality for bypass substitutes

Computed tomography angiography: vital if surgical management is being planned as it is more accurate than ultrasound in determining the precise anatomy and degree of stenosis- MRA if pregnant or have CKD and cant take contrast

18
Q

apart form Imaging and ABPI which other primary investigations would you do for patients?

A

ECG, FBC, U&E, random glucose or HbA1c, serum cholesterol and lipid profiles

19
Q

how is PAD managed?

A
  1. lifestyle:
    - specialised exercise programme
    - control of cardiovascular risk factors
  2. medical
    - 75mg clopidigrel for prevention of cardiovascular complications
    - naftidrofuryl oxalate vasodilator if not responding to exercise and lifestyle measures, plus dont want surgery
  3. Surgical
    - refer if no improvement after 3 months of lifestyle therapy
    - endovascular surgery
    - bypass surgery