Peripheral Arterial and Venous Disease Flashcards
Where are the deep and superficial veins in the lower limb found
Deep - deep to the deep fasica
Superficial - found within subcutaneous tissue
Name the deep veins of the lower limb
Popliteal vein
Femoral vein
External iliac vein
Name the superficial veins of the lower limb
Short and long saphenous veins
What are varicose veins and why do they form
Tortuous, twisted or lengthened veins
Dilatation of vein wall and separation of valve cusps causes them to become incompetent so blood flows backwards, causing the veins to enlarge
Due to inherent weakness of vein wall
What are the symptoms of varicose veins
Varicose veins themselves
Heaviness
Tension
Aching
Itching
What are the complications of varicose veins
Haemorrhage of the vein
Thrombophlebitis
Venous hypertension causes:
- Oedema
- Skin pigmentation
- Varicose eczema
- Lipodermatosclerosis
- Venous ulceration
What is thrombophlebitis
Inflammation of a vein due to a thombus
The venous thrombus initiates an inflammatory response
What causes haemosiderin staining
This is due to the venous hypertension
This causes RBCs to leave blood vessels and enter tissue fluid where they are taken up by macrophages and are oxidised
This causes oxidation of the iron in Hb causing the dark staining of the skin
What is lipodermatosclerosis
Thickening of the fat in the skin, the fat thickens and hardens
What causes venous ulceration
Venous hypertension
What are the causes of muscle pump failure
Failure of calf muscle contraction - immobility, obesity (tend to shuffle so not using muscles), reduced hip, knee and/or ankle movement
Deep vein incompetence
Volume overload - superficial vein incompetence
What are the likely reasons for arterial and venous thrombosis
Arterial - change in lining of vessel wall
Venous - changes in flow of blood
How does arterial thombus formation differ from venous thrombus formation
Arterial needs platelets and activation of both pathways
Venous needs intrinsic pathway initially, then activation of the both pathways
Arterial thrombi are platelet rich, venous thrombi are fibrin rich
Which type of prophylactics should be used to prevent the different types of thromi formation
For arterial thrombi, use anti-platelet
For venous thrombi, use anti-coagulant
Where does a DVT commonly begin and what response does it produce
Commonly begins in deep calf veins
Produces an inflammatory response