Perioperative Obstructive Sleep Apnea (OSA) Flashcards

1
Q

What are the primary physical causes of OSA in adults? And in children?

A

Adults: obesity

Children: tonsils hypertrophy or enlargement

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2
Q

Approximately how many muscles are in the pharynx?

A

More than 20.

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3
Q

During sleep, neuronal stimulation to which muscles are decreased?

A

pharyngeal dilator muscles

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4
Q

During which cycle of sleep do we see the most decrease in neuronal stimulation to the pharyngeal dilator muscles?

A

REM sleep

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5
Q

What are some functions of the pharynx?

A
  • funnel food to esophagus
  • speech resonator for phonation
  • channel for respiratory airflow
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6
Q

T/F. The pharynx is not supported by bony musculature.

A

True

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7
Q

What are the two animal species that could have OSA?

A
  • flat-faced dogs (eg. bugs, bull dogs)
  • humans
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8
Q

Name 3 areas of airway collapse. Which one is the most common?

A
  • retropalatal: most common
  • retroglossal
  • hypopharyngeal
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9
Q

What are the biomechanical forces supporting airway patency?

A
  • neuronal stimulation to the pharyngeal dilators
  • low extra-luminal pressure
  • higher lung volumens
  • posture
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10
Q

What are the biomechanic forces opposing airway patency?

A
  • low lung volumes: eg. morbidly obese pt with low FRC
  • increased extra-luminal pressure: eg. with redundant tissue
  • supine position
  • residual neuromuscular blockade
  • sedatives and narcotics
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11
Q

T/F. OSA is the most common sleep disorder in adults.

A

True

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12
Q

____% of males and ____% of females have OSA.

A

11.4% males, 4.7% females

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13
Q

Define apnea and hypopnea.

A

Apnea: cessation or total obstruction of breathing

Hypopnea: reduction in breathing death or frequency

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14
Q

What are some cardic co-morbid conditions with sleep apnea?

A
  • hypertension
  • bi-ventricular heart failure
  • ischemic heart diseases
  • atrial fibrillation
  • cardiac dysrhythmias
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15
Q

What are some pulmonary co-morbid conditions with sleep apnea?

A
  • asthma
  • pulmonary hypertension
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16
Q

What are some neurological co-morbid conditions with sleep apnea?

A
  • transient ischemic attack
  • cerebral vascular accident
17
Q

What are some neurocognitive co-morbid conditions with sleep apnea?

A
  • daytime hyper-somnolence: chronically tired or fatigue bc of not getting good sleep
  • memory impairment
  • concentration difficulties
18
Q

What are some hormonal(endocrine) and metablic co-morbid conditions with sleep apnea?

A
  • DM II
  • Metabolic syndrome
  • hypothroidism
  • cortisol, stress hormone dysregulation
  • obesity
  • Pickwickian syndrome: “Fat Boy”; obese, chronically tired, snored loudly, HTN, DM, CHF
19
Q

Name the risk factors for OSA.

A
  • male gender
  • smokers
  • obesity
  • older patients
20
Q

What is the Apnea-Hypopnea Index (AHI)?

A

Total number of obstructions per hour of sleep

21
Q

Name the 3 OSA classifications and their respective AHI critera.

A
  • Mild: 5-15 AHI
  • Moderate: 15-30 AHI
  • Severe: >30 AHI
22
Q

OSA Screening

S_____

T_____

O_____

P_____

High risk for OSA with ___ or more criteria.

A

Snoring

Tired

Observed apnea

Pressure elevation

2 or more- high risk for OSA

23
Q

OSA Screening

B____

A____

N____

G____

A

BMI > 35

Age > 50

Neck circumference > 40cm

Gender= male

High risk for OSA with 3 or more (STOP-BANG)

24
Q

What does it mean when the STOP-BANG Screening has a specificity of 43%?

A

It means a fair number of ppl tested postive on STOP-BANG, but yet have a negative in-house sleep study.

“False Positive”

25
What is the gold standard for OSA diagnosis? And why is it useful?
A polysomnography. For diagnosis and classification of severity, and titration of CPAP
26
What is the prevalence of OSA in general population? What percent of patients presenting for surgery with OSA are undiagnosed?
2-25%. 70-80%
27
What are some post-operative adverse outcomes of patients with sleep apnea?
- hypoxia - respiratory arrest - ischemia - delirium - cardiac arrest - death
28
Describe the OSA Arrest Loop
Snoring or snorking(profound snoring, almost completely obstructed) -\> self-correcting apnea -\> non-self correcting apnea -\> decreased level of consciousness
29
Ways for OSA Risk Reduction
Patient screening, classification, and treatment Pre and Post-Op CPAP compliance Prolonged PACU Observation In-patient oximetry, capnography, ECG monitoring
30
Patient with OSA are more sensitive to which type of drugs?
Benzodiazepines. They depress CNS activity and increase in supraglottic airway resistance.
31
Which anesthetic agent has shown to increase obstruction when used with propofol?
Isoflurane
32
Propofol, when added with which anesthetic gas, increase incidence in postoperative desaturation?
Isoflurane
33
What is unique about the drug clonidine? Name one other analog.
- decreased perioperative anesthetics and analgesic requirements - sedation - analgesia - maintain respiratory drive - dexmedetomidine
34
What are some recommendations for OSA patients presenting for surgery?
- Pts who screen at risk should undergo polysomnography to access severity - CPAP or BiPAP in the perioperative period - perioperative weight loss - preoperative medication - preoperative use of mandbular advancement or oral supplies