periodontal microbiology Flashcards

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1
Q

Biofilm development stages

A
  • adhesion
  • colonisation
  • accumulation
  • complex community
  • dispersal
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2
Q

P Gingivalis virulence factors

A
  • host cell tissue adherence and invasion
  • elaboration of proteases
  • endotoxin
  • capsular polysaccharide
  • tissue toxic metabolic by-products e.g. ammonia
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3
Q

how does p gingival manipulate host defences?

A

biofilm
ginigpains
induction of tissue destruction
subversion

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4
Q

How gingipains manipulate host defences

A
  • degradation of innate receptors
  • degradation of cytokines
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5
Q

Periodontal disease systemic implications

A
  • increased risk of cardiovascular disease
  • suggested increased risk of rheumatoid arthritis
  • up to 6 fold increased risk of diabetes
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6
Q

Periodontal disease systemic implications

A
  • increased risk of cardiovascular disease
  • suggested increased risk of rheumatoid arthritis
  • up to 6 fold increased risk of diabetes
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7
Q

important microbes in gingivitis

A

actinomyces
prevotella intermedia
bacteroides
fusobacterium nucleatum

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8
Q

periodontitis microbes

A
  • P. gingival
  • T. forsythia
  • T. denticola
  • p. intermedia
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9
Q

P gingival features

A

gram negative bacteria
non-motile rod
strict anaerobe
black pigmentation

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10
Q

Periodontal disease - systemic implications

A

increased risk of cardiovascular disease
increased risk of diabetes up to 6 fold
suggested increased risk of rheumatoid arthritis

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