Pericardial disease Flashcards
First line treatment of acute pericarditis
Cochicine 0.6 mg daily (<70 kg) or BID (= 70 kg) for 3 months + NSAID (typically high-dose aspirin three times a day or ibuprofen).
If NSAID CI, then steroids.
effusive-constrictive pericarditis
Failure of the right atrial pressure to fall by 50% or to a level <10 mm Hg after pericardiocentesis
incidental pericardial effusion
CRP-> treat for acute pericarditis if elevated
labwork for confirmed pericarditis
get troponin to rule out myopericarditis
most common etiology of pericarditis in developing countries.
clinical recurrent pericarditis.
TB.
just treat with colchicine+NSAID without further testing.
refractory pericarditis treatment
azathioprine, intravenous immunoglobulin
most important in predicting hemodynamic consequences of a pericardial effusion
rate of accumulation
elevated right heart filling pressures with Kussmaul’s sign (jugular venous distension without inspiratory decline)
constrictive pericarditis. If there’s LGE on MRI, need to use anti-inflammatories too.
young woman with facial flushing, myalgia+ pericarditis
get ANA
constrictive pericarditis echo
> 30% inspiratory drop in the mitral inflow velocities , interventricular septal “bounce”, expiratory diastolic flow reversal in hepatic veins
pericarditis workup
blood work, CXR, EKG, Echo
recurrent malignant pericardial effusion
window not pericardiocentesis
Most sensitive diagnostic factor for tamponade
IVC dilation. If absent-> not tamponade
hypotension, jugular venous distention, and decreased heart sounds
Beck’s triad, tamponade, TTE is first line test