Performance Analysis Questions

Question 1

What is the risk of long QT syndrome/

Answer 1

Ventricular tachycardia/torsafe de pointes -> collapse and sudden death

Question 2

What are the most common variants of long QT syndrome?

Answer 2

LQT1 and LQT2

Question 3

What causes the common variants of long QT syndrome?

Answer 3

Defects in alpha subunit of slow delayed potassium channels

Question 4

What are the congenital causes of prolonged QT?

Answer 4

Jervell-Lange-Nielsen syndrome (+deafness)

Romano-Ward syndrome (no deafness)

Question 5

What are the drug causes of prolonged QT?

Answer 5

Amiodarone, sotalol, class 1a antiarrhtyhmic drugs, TCAs, SSRIs, methadone, chloroquine, terfenadine, erythromycin, haloperidol, ondansetron

Question 6

What are the electrolyte causes of prolonged QT?

Answer 6

Hypocalcaemia, hypokalaemia, hypomagnesaemia

Question 7

How is high risk long QT syndrome managed?

Answer 7

Implantable cardioverter defibrillators, B-blockers

Question 8

What should all patients be given post STEMI?

Answer 8

Aspirin, P2Y12-receptor antagonist like clopidogrel