peptic ulcer disease Flashcards
what are the types of peptic ulcer disease
acute or chronic
gastric or duodenal
stress related
medication induced
what is acute peptic ulcer disease
superficial erosison
minimal inflmmation
short duration
what is chronic peptic ulcer disease
long duration
muscular wall erosion
for many months
more common than acute
when do peptic ulcer delelop
only in the presence of acid envionrment
when do stress related mucosal disease happen
acute ulcers that develop after major physiologic insult
gastric ulcers are more prevalent in
women
peak incidence of gastric ulcers
> 50 years of age
gastric secretion in gastric ulcer
normal to decreased
when do gastric ulcer pain usually happen
1-2 hours after meals
what are risk factors for gastric ulcers
H. pylori
medications
bile reflux
when do duodenal ulcers usually occur
increase between ages of 35-45 years
H. pylori is found in
90-95% of patients
what do increased risk of duodenal ulcers
COPD cirrhosis of liver chronic pancreaitis hyperparathyroidism chronic kidney disease zollinger ellison syndrome
when does pain start with duodenal ulcers
2-5 hours after meal
burning or cramp like
what is the gastric secretion of duodenal ulcer
increase
what are the 3 majors complications of ulcers
hemorrhage
perforation
gastric outlet obstruction
ALL EMERGENCY SITUATION
what is the most common complication of peptic ulcer disease
hemorrhage
most lethal complicaiton
what do we do with large perforations
immediate surgical closure
what do we do with small perforation
spontaneoulsy seal themselves
what are clinical manifestation of perfoartion
sudden onset pain radiates to back rigid broadlike abdominal muscles shallow rapid respirations tachycardia weak pulse bowel sound absent nausea vomiting
bacterial peritonitis may occur within
6-12 hours after perforation
which diagnostic studies is most accurate
endoscopy
what are noninvasive tests of H. pylori
urea breath test
stool antigen test
serum or whole blood antibody tests
who is barium contrast study reserved for
people who cannot undergo endoscopy
