Peptic ulcer disease

Question 1

What are the 2 types of peptic ulcer disease namely speaking?

Answer 1

Gastric ulcers

Duodenal ulcers

Question 2

What is the difference between gastric and duodenal ulcers in presentation

Answer 2

Gastric ulcers - pain worse on eating
Duodenal ulcers - pain relieved by eating

Features of upper GI haemorrhage may be seen: hematemesis, melaena

Question 3

Gold standard investigation for peptic ulcer disease?

Answer 3

Gastroscopy +/- Duodenoscopy

Question 4

Give 4 risk factors for peptic ulcer disease?

Answer 4

H.pylori infection
Smoking
Alcohol
NSAID use

Question 5

What are 4 tests can you do for H.pylori?

Answer 5

Urease breath test (better, less invasive and more accurate) –> can be used to confirm eradication of the organism
H.pylori stool antigen test
Endoscopy + biopsy
H.pylori serology

Question 6

3 complications of peptic ulcer disease?

Answer 6

Perforation
Upper GI bleed
Gastric outlet obstruction
Iron deficiency anaemia