Pentose Phosphat Pathway Flashcards

1
Q

Hvor foregår pentose phosphat pathway?

A

I cytoplasma

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2
Q

Formålet med processen

A

At danne ribose-5-phosphat som er precursor for mange molekyler f.eks. nukleotider, coenzymer og nukleinsyrer

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3
Q

Samlede reaktion

A

Glukose-6-phosphat + H2O + 2NADP+ -> ribose-5-phosphat + CO2 + 2NADPH + 2H+

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4
Q

Er den oxidative pentose pathway reversibel eller irreversibel?

A

Irreversibel (den har en lav negativ dG-værdi)

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5
Q

Hvad afgør om glukose-6-phosphat indgår i glykolysen eller pentose pathway?

A

Koncentrationen af cytosolisk NADP+, fa den første reaktion i pentose pathway kræver NADP+

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6
Q

Hvad er formålet med den nonoxidative fase?

A

Danne glykose-6-phosphat

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7
Q

Hvordan kan pentose pathway hæmmes?

A

NADPH hæmmer pathwayen

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